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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-NEDD4-2 Antibody (3Y211)

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货号 TMAB-09336

Anti-NEDD4-2 Antibody (3Y211) 是一种 Rabbit 抗体，靶向 NEDD4-2。Anti-NEDD4-2 Antibody (3Y211) 可用于 WB,IP。

Anti-NEDD4-2 Antibody (3Y211)

Anti-NEDD4-2 Antibody (3Y211)

一键复制产品信息
Rating icon 还可以
货号 TMAB-09336

Anti-NEDD4-2 Antibody (3Y211) 是一种 Rabbit 抗体，靶向 NEDD4-2。Anti-NEDD4-2 Antibody (3Y211) 可用于 WB,IP。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-NEDD4-2 Antibody (3Y211) is a Rabbit antibody targeting NEDD4-2. Anti-NEDD4-2 Antibody (3Y211) can be used in WB,IP.
Ig Type
IgG
克隆号
3Y211
反应种属
Human (predicted:Mouse,Rat)
应用WBIP
推荐剂量
WB: 1:500-2000; IP: 1:20-50
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. May be recruited to exosomes by NDFIP1.
组织特异性Ubiquitously expressed, with highest levels in prostate, pancreas and kidney.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景E3 ubiquitin-protein ligase that mediates the polyubiquitination of lysine and cysteine residues on target proteins and is thereby implicated in the regulation of various signaling pathways including autophagy, innate immunity or DNA repair.
抗原信息
免疫原
A synthesized peptide: human NEDD4L
抗原种属
Human
基因名称
NEDD4L
基因ID
23327
蛋白名称
E3 ubiquitin-protein ligase NEDD4-like
Uniprot ID
Q96PU5
功能
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits TGF-beta signaling by triggering SMAD2 and TGFBR1 ubiquitination and proteasome-dependent degradation. Promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5. Promotes ubiquitination and degradation of SGK1 and TNK2.
化学信息
分子量Theoretical: 112 kDa. Actual: 130 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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