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顶部生物活性储存和溶解信息计算器

Anti-RAP1GAP Antibody (4C780)

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产品编号 TMAC-03533
别名 RPGP1_HUMAN, RAPGAP, RAP1GAPII, Rap1GAP1, Rap1GAP, Rap1ga1 protein, RAP1GA1, Rap1 GTPase-activating protein 1, Rap1 GTPase activating protein 1, RAP1 GTPase activating protein, KIAA0474

Anti-RAP1GAP Antibody (4C780) 是一种 Mouse 抗体，靶向 RAP1GAP。Anti-RAP1GAP Antibody (4C780) 可用于 FCM,WB。

Anti-RAP1GAP Antibody (4C780)

Anti-RAP1GAP Antibody (4C780)

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产品编号 TMAC-03533 别名 RPGP1_HUMAN, RAPGAP, RAP1GAPII, Rap1GAP1, Rap1GAP, Rap1ga1 protein, RAP1GA1, Rap1 GTPase-activating protein 1, Rap1 GTPase activating protein 1, RAP1 GTPase activating protein, KIAA0474

Anti-RAP1GAP Antibody (4C780) 是一种 Mouse 抗体，靶向 RAP1GAP。Anti-RAP1GAP Antibody (4C780) 可用于 FCM,WB。

规格价格库存数量
50 μL
¥ 1,985
5日内发货
100 μL
¥ 2,995
5日内发货
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产品介绍

生物活性
产品描述
Anti-RAP1GAP Antibody (4C780) is a Mouse antibody targeting RAP1GAP. Anti-RAP1GAP Antibody (4C780) can be used in FCM,WB.
别名RPGP1_HUMAN, RAPGAP, RAP1GAPII, Rap1GAP1, Rap1GAP, Rap1ga1 protein, RAP1GA1, Rap1 GTPase-activating protein 1, Rap1 GTPase activating protein 1, RAP1 GTPase activating protein, KIAA0474
克隆号
4C780
交叉反应
Human
验证活性
1. Western blot analysis of RAP1GAP on human RAP1GAP recombinant protein using anti-RAP1GAP antibody at 1/1,000 dilution.
2. Western blot analysis of RAP1GAP on HEK293 (1) and RAP1GAP-hIgGFc transfected HEK293 (2) cell lysate using anti-RAP1GAP antibody at 1/1,000 dilution.
3. Flow cytometric analysis of A431 cells with RAP1GAP antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).
verifiedActivityverifiedActivityverifiedActivity
应用FCMWB
推荐剂量
WB: 1:500-2000; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Rap1 GTPase activating protein (Rap1GAP) specifically stimulates GTP hydrolytic activity of the monomeric G protein Rap1. Physical interaction between Gα z, a member of the Gi family of trimeric G proteins, and Rap1GAP blocks the ability of regulators of G protein signaling to stimulate GTP hydrolysis of the α subunit, and also attenuates the ability of activated Gα z to inhibit adenylyl cyclase. Rap1GAP is expressed in the brain, kidney and pancreas and may act as a signal integrator to coordinate and/or integrate Gz signaling and Rap1 signaling in cells. A novel isoform of Rapl GTPase-activating protein, designated Rap1GAPII, binds specifically to Gα z. Stimulation of the Gi-coupled M2 Muscarinic receptor translocates Rap1GAPII from the cytosol to the membrane and decreases the amount of GTP-bound Rap1, resulting in the activation of ERK/MAPK.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
P47736
化学信息
分子量Theoretical: 73 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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