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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-CD156B Monoclonal Antibody (3Z451)

Synonyms: TACE, NISBD1, NISBD, CSVP, ADAM18, ADAM17
货号 TMAT-0280 一键复制产品信息
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Anti-CD156B Monoclonal Antibody (3Z451) 是一种 Mouse 抗体，靶向 CD156B。Anti-CD156B Monoclonal Antibody (3Z451) 可用于 WB,IF,FCM。

Anti-CD156B Monoclonal Antibody (3Z451)

一键复制产品信息
Rating icon 还可以
货号 TMAT-0280

别名 TACE, NISBD1, NISBD, CSVP, ADAM18, ADAM17

Anti-CD156B Monoclonal Antibody (3Z451) 是一种 Mouse 抗体，靶向 CD156B。Anti-CD156B Monoclonal Antibody (3Z451) 可用于 WB,IF,FCM。

Anti-CD156B Monoclonal Antibody (3Z451)
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产品介绍

生物活性
产品描述
Anti-CD156B Monoclonal Antibody (3Z451) is a Mouse antibody targeting CD156B. Anti-CD156B Monoclonal Antibody (3Z451) can be used in WB,IF,FCM.
别名
TACE, NISBD1, NISBD, CSVP, ADAM18, ADAM17
Ig Type
IgG1
克隆号
3Z451
反应种属
Human, Mouse
应用WBIFFCM
推荐剂量
WB: 1/500-1/2000; IF: 1/200-1/1000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/ml
研究背景This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded preproprotein is proteolytically processed to generate the mature protease. The encoded protease functions in the ectodomain shedding of tumor necrosis factor-alpha, in which soluble tumor necrosis factor-alpha is released from the membrane-bound precursor. This protease also functions in the processing of numerous other substrates, including cell adhesion proteins, cytokine and growth factor receptors and epidermal growth factor (EGF) receptor ligands, and plays a prominent role in the activation of the Notch signaling pathway. Elevated expression of this gene has been observed in specific cell types derived from psoriasis, rheumatoid arthritis, multiple sclerosis and Crohn's disease patients, suggesting that the encoded protein may play a role in autoimmune disease. Additionally, this protease may play a role in viral infection through its cleavage of ACE2, the cellular receptor for SARS-CoV and SARS-CoV-2.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human CD156B (AA: 497-671) expressed in E. Coli.
抗原种属
Human
基因名称
ADAM17
基因ID
6868
蛋白名称
Disintegrin and metalloproteinase domain-containing protein 17
Uniprot ID
P78536
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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