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Anti-Phospho-Presenilin 2 (Ser330) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-Presenilin 2 (Ser330)。Anti-Phospho-Presenilin 2 (Ser330) Polyclonal Antibody 可用于 WB,IHC-P,IF(paraffin section),ELISA。
Anti-Phospho-Presenilin 2 (Ser330) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-Presenilin 2 (Ser330)。Anti-Phospho-Presenilin 2 (Ser330) Polyclonal Antibody 可用于 WB,IHC-P,IF(paraffin section),ELISA。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,495 | 5日内发货 | |
100 μL | ¥ 2,245 | 5日内发货 |
产品描述 | Anti-Phospho-Presenilin 2 (Ser330) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Presenilin 2 (Ser330). Anti-Phospho-Presenilin 2 (Ser330) Polyclonal Antibody can be used in WB,IHC-P,IF(paraffin section),ELISA. |
别名 | Presenilin 2 (p-Ser330), Presenilin 2 (p-S330), p-Presenilin 2 (Ser330), p-Presenilin 2 (S330) |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
应用 | |
推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-300; ELISA: 1:5000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
性状 | Liquid |
缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
研究背景 | presenilin 2(PSEN2) Homo sapiens Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1 or PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor such that, they either directly regulate gamma-secretase activity, or themselves act are protease enzymes. Two alternatively spliced transcript variants encoding different isoforms of PSEN2 have been identified. [provided by RefSeq, Jul 2008], |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | A synthesized phosphopeptide: human Presenilin 2 around the phosphorylation site of Ser330. AA range:296-345 |
抗原种属 | human |
Uniprot ID |
分子量 | Actual: 50 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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