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Anti-Phospho-Presenilin 2 (Ser330) Polyclonal Antibody

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Anti-Phospho-Presenilin 2 (Ser330) Polyclonal Antibody
产品编号 TMAC-03419
别名 Presenilin 2 (p-Ser330), Presenilin 2 (p-S330), p-Presenilin 2 (Ser330), p-Presenilin 2 (S330)

Anti-Phospho-Presenilin 2 (Ser330) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-Presenilin 2 (Ser330)。Anti-Phospho-Presenilin 2 (Ser330) Polyclonal Antibody 可用于 WB,IHC-P,IF(paraffin section),ELISA。

Anti-Phospho-Presenilin 2 (Ser330) Polyclonal Antibody

Anti-Phospho-Presenilin 2 (Ser330) Polyclonal Antibody

Rating icon 还可以
Anti-Phospho-Presenilin 2 (Ser330) Polyclonal Antibody
产品编号 TMAC-03419 别名 Presenilin 2 (p-Ser330), Presenilin 2 (p-S330), p-Presenilin 2 (Ser330), p-Presenilin 2 (S330)

Anti-Phospho-Presenilin 2 (Ser330) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-Presenilin 2 (Ser330)。Anti-Phospho-Presenilin 2 (Ser330) Polyclonal Antibody 可用于 WB,IHC-P,IF(paraffin section),ELISA。

规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,245
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-Presenilin 2 (Ser330) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Presenilin 2 (Ser330). Anti-Phospho-Presenilin 2 (Ser330) Polyclonal Antibody can be used in WB,IHC-P,IF(paraffin section),ELISA.
别名Presenilin 2 (p-Ser330), Presenilin 2 (p-S330), p-Presenilin 2 (Ser330), p-Presenilin 2 (S330)
Ig Type
IgG
交叉反应
Human,Mouse,Rat
应用
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-300; ELISA: 1:5000
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
性状Liquid
缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
研究背景presenilin 2(PSEN2) Homo sapiens Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1 or PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor such that, they either directly regulate gamma-secretase activity, or themselves act are protease enzymes. Two alternatively spliced transcript variants encoding different isoforms of PSEN2 have been identified. [provided by RefSeq, Jul 2008],
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
A synthesized phosphopeptide: human Presenilin 2 around the phosphorylation site of Ser330. AA range:296-345
抗原种属
human
Uniprot ID
化学信息
分子量Actual: 50 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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