BAFFR/TNFRSF13C Protein, Human, Recombinant (hFc & His) is expressed in HEK293 Cells. The accession number is Q96RJ3-1.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μg | ¥ 3,820 | 期货 | |
| 1 mg | 待询 | 期货 |
| 生物活性 | Immobilized BAFF/BLyS Protein, Human, Recombinant (hFc) (Cat#TMPY-01239) at 2 μg/ml (100 μl/well) can bind BAFFR/TNFRSF13C Protein, Human, Recombinant (hFc & His) (Cat#TMPY-07137), the EC50 is 30-100 ng/mL. |
| 产品描述 | BAFFR/TNFRSF13C Protein, Human, Recombinant (hFc & His) is expressed in HEK293 Cells. The accession number is Q96RJ3-1. |
| 种属 | Human |
| 表达系统 | HEK293 Cells |
| 标签 | C-His, N-hFc |
| 蛋白编号 | Q96RJ3-1 |
| 别名 | prolixin,CVID4,CD268,BROMIX,BR3,BAFF-R,BAFFR |
| 蛋白构建 | A DNA sequence encoding the Human TNFRSF13C (NP_443177.1) (Arg6-Ala71) was fused with a polyhistidine tag at the C-terminus and the Fc region of human IgG1 at the N-terminus. |
| 蛋白纯度 | ≥ 95% as determined by SDS-PAGE. ≥ 95% as determined by SEC-HPLC. |
| 分子量 | 36.59 kDa (predicted); 49.8 kDa (reducing contition, due to glycosylation) |
| 内毒素 | < 1.0 EU per μg of the protein as determined by the LAL method |
| 缓冲液 | Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 复溶方法 | Please refer to the lot-specific COA. |
| 存储 | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. |
| 研究背景 | Tumor necrosis factor receptor superfamily, member 13C (TNFRSF13C) also known as B-cell-activating factor receptor (BAFFR) and CD268 antigen, is a member of the tumor necrosis factor receptor superfamily. A tumor necrosis factor receptor (TNFR), or death receptor, is a trimeric cytokine receptor that binds tumor necrosis factors (TNF). The receptor cooperates with an adaptor protein which is important in determining the outcome of the response. Members of the TNF receptor superfamily (TNFRSF) have crucial roles in both innate and adaptive immunity and in cellular apoptosis process. Apoptosis is a cell suicide mechanism that enables metazoans to control cell number in tissues and to eliminate individual cells that threaten the animal's survival. Certain cells have unique sensors, termed death receptors or tumour necrosis factor (TNFR), on their surface. Tumour necrosis factors (TNFR) detect the presence of extracellular death signals and, in response, they rapidly ignite the cell's intrinsic apoptosis machinery. It has been proposed that abnormally high levels of BAFFR/TNFRSF13C (CD268) may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. |
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