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Anti-ALAS2 Antibody (2M567) 是一种 Mouse 抗体,靶向 ALAS2。Anti-ALAS2 Antibody (2M567) 可用于 WB,IP,IF,IHC-P。
Anti-ALAS2 Antibody (2M567) 是一种 Mouse 抗体,靶向 ALAS2。Anti-ALAS2 Antibody (2M567) 可用于 WB,IP,IF,IHC-P。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,990 | 5日内发货 | |
100 μL | ¥ 2,985 | 5日内发货 |
产品描述 | Anti-ALAS2 Antibody (2M567) is a Mouse antibody targeting ALAS2. Anti-ALAS2 Antibody (2M567) can be used in WB,IP,IF,IHC-P. |
别名 | XLSA, XLEPP, XLDPP, SIDBA1, RP23-338A17.1, OTTMUSP00000020679, OTTHUMP00000023389, OTTHUMP00000023388, mitochondrial, HEM0_HUMAN, FLJ93603, erythroid-specific, Erythroid specific ALAS, Delta-aminolevulinate synthase 2, Delta-ALA synthase 2, Delta aminolevulinate synthase 2, Delta aminolevulinate synthase, Delta ALA synthetase, Delta ALA synthase 2, ASB, ANH1, Aminolevulinic acid synthase 2, erythroid, Aminolevulinate delta synthase 2, ALAS-E, ALASE, Alas2, ALAS, erythroid, ALAS E, Alas 2, ALAS, 5-aminolevulinic acid synthase 2, 5-aminolevulinate synthase, 5 aminolevulinic acid synthase 2, 5 aminolevulinic acid synthase, 5 aminolevulinate synthase erythroid specific mitochondrial, 5 aminolevulinate synthase 5 aminolevulinate synthase 2, 5 aminolevulinate synthase 2, 5 @aminolevulinate synthase erythroid specific |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of ALAS-E expression in non-transfected (A)and human ALAS-E transfected (B) 293T whole cell lysates. 2. Immunoperoxidase staining of formalin fixed, paraffin-embedded human cervix tissue showing cytoplasmic staining of squamous epithelial cells. |
应用 | |
推荐剂量 | WB: 1:100-1000; IHC-P: 1:50-500; IP: 1-2 μg per 100-500 μg of total protein (1 ml of cell lysate) |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | Hybridoma Monoclonal Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | 5-aminolevulinate synthase 1 (ALAS-H) and 2 (ALAS-E) are two isoforms of ALAS, an enzyme catalyzing the first step of the heme biosynthetic pathway in mammals. The erythroid-specific isoenzyme, ALAS-E, regulates the first step of hematopoietic cell differentation and iron metabolism in the liver. ALAS-H is a housekeeping protein which mediates synthesis of early heme in the mitochondria of most cells. Succinyl CoA associates with ALAS-E in protein conformation change and translocation of ALAS-E into the mitochondria and does not interact with ALAS-H. The ALAS-E 5'-flanking region contains binding sites for nuclear activators such as GATA-1, NF-E2 and EKLF. Since the ALAS gene maps to the X chromosome, mutation of the gene leads to the pyridoxine-refractory X-linked sideroblastic anemia. |
偶联 | Unconjugated |
免疫原 | Peptide |
Uniprot ID |
分子量 | Theoretical: 60 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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