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Anti-ALAS2 Antibody (2M567)

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Anti-ALAS2 Antibody (2M567)
产品编号 TMAC-00131
别名 XLSA, XLEPP, XLDPP, SIDBA1, RP23-338A17.1, OTTMUSP00000020679, OTTHUMP00000023389, OTTHUMP00000023388, mitochondrial, HEM0_HUMAN, FLJ93603, erythroid-specific, Erythroid specific ALAS, Delta-aminolevulinate synthase 2, Delta-ALA synthase 2, Delta aminolevulinate synthase 2, Delta aminolevulinate synthase, Delta ALA synthetase, Delta ALA synthase 2, ASB, ANH1, Aminolevulinic acid synthase 2, erythroid, Aminolevulinate delta synthase 2, ALAS-E, ALASE, Alas2, ALAS, erythroid, ALAS E, Alas 2, ALAS, 5-aminolevulinic acid synthase 2, 5-aminolevulinate synthase, 5 aminolevulinic acid synthase 2, 5 aminolevulinic acid synthase, 5 aminolevulinate synthase erythroid specific mitochondrial, 5 aminolevulinate synthase 5 aminolevulinate synthase 2, 5 aminolevulinate synthase 2, 5 @aminolevulinate synthase erythroid specific

Anti-ALAS2 Antibody (2M567) 是一种 Mouse 抗体,靶向 ALAS2。Anti-ALAS2 Antibody (2M567) 可用于 WB,IP,IF,IHC-P。

Anti-ALAS2 Antibody (2M567)

Anti-ALAS2 Antibody (2M567)

Rating icon 还可以
Anti-ALAS2 Antibody (2M567)
产品编号 TMAC-00131 别名 XLSA, XLEPP, XLDPP, SIDBA1, RP23-338A17.1, OTTMUSP00000020679, OTTHUMP00000023389, OTTHUMP00000023388, mitochondrial, HEM0_HUMAN, FLJ93603, erythroid-specific, Erythroid specific ALAS, Delta-aminolevulinate synthase 2, Delta-ALA synthase 2, Delta aminolevulinate synthase 2, Delta aminolevulinate synthase, Delta ALA synthetase, Delta ALA synthase 2, ASB, ANH1, Aminolevulinic acid synthase 2, erythroid, Aminolevulinate delta synthase 2, ALAS-E, ALASE, Alas2, ALAS, erythroid, ALAS E, Alas 2, ALAS, 5-aminolevulinic acid synthase 2, 5-aminolevulinate synthase, 5 aminolevulinic acid synthase 2, 5 aminolevulinic acid synthase, 5 aminolevulinate synthase erythroid specific mitochondrial, 5 aminolevulinate synthase 5 aminolevulinate synthase 2, 5 aminolevulinate synthase 2, 5 @aminolevulinate synthase erythroid specific

Anti-ALAS2 Antibody (2M567) 是一种 Mouse 抗体,靶向 ALAS2。Anti-ALAS2 Antibody (2M567) 可用于 WB,IP,IF,IHC-P。

规格价格库存数量
50 μL
¥ 1,990
5日内发货
100 μL
¥ 2,985
5日内发货
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产品介绍

生物活性
产品描述
Anti-ALAS2 Antibody (2M567) is a Mouse antibody targeting ALAS2. Anti-ALAS2 Antibody (2M567) can be used in WB,IP,IF,IHC-P.
别名XLSA, XLEPP, XLDPP, SIDBA1, RP23-338A17.1, OTTMUSP00000020679, OTTHUMP00000023389, OTTHUMP00000023388, mitochondrial, HEM0_HUMAN, FLJ93603, erythroid-specific, Erythroid specific ALAS, Delta-aminolevulinate synthase 2, Delta-ALA synthase 2, Delta aminolevulinate synthase 2, Delta aminolevulinate synthase, Delta ALA synthetase, Delta ALA synthase 2, ASB, ANH1, Aminolevulinic acid synthase 2, erythroid, Aminolevulinate delta synthase 2, ALAS-E, ALASE, Alas2, ALAS, erythroid, ALAS E, Alas 2, ALAS, 5-aminolevulinic acid synthase 2, 5-aminolevulinate synthase, 5 aminolevulinic acid synthase 2, 5 aminolevulinic acid synthase, 5 aminolevulinate synthase erythroid specific mitochondrial, 5 aminolevulinate synthase 5 aminolevulinate synthase 2, 5 aminolevulinate synthase 2, 5 @aminolevulinate synthase erythroid specific
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of ALAS-E expression in non-transfected (A)and human ALAS-E transfected (B) 293T whole cell lysates.
2. Immunoperoxidase staining of formalin fixed, paraffin-embedded human cervix tissue showing cytoplasmic staining of squamous epithelial cells.
应用
推荐剂量
WB: 1:100-1000; IHC-P: 1:50-500; IP: 1-2 μg per 100-500 μg of total protein (1 ml of cell lysate)
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景5-aminolevulinate synthase 1 (ALAS-H) and 2 (ALAS-E) are two isoforms of ALAS, an enzyme catalyzing the first step of the heme biosynthetic pathway in mammals. The erythroid-specific isoenzyme, ALAS-E, regulates the first step of hematopoietic cell differentation and iron metabolism in the liver. ALAS-H is a housekeeping protein which mediates synthesis of early heme in the mitochondria of most cells. Succinyl CoA associates with ALAS-E in protein conformation change and translocation of ALAS-E into the mitochondria and does not interact with ALAS-H. The ALAS-E 5'-flanking region contains binding sites for nuclear activators such as GATA-1, NF-E2 and EKLF. Since the ALAS gene maps to the X chromosome, mutation of the gene leads to the pyridoxine-refractory X-linked sideroblastic anemia.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Peptide
Uniprot ID
化学信息
分子量Theoretical: 60 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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