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Anti-SIRT2 Antibody (2G702)
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产品编号 TMAC-03762
别名 Sirtuin type 2, Sirtuin 2, Sirtuin (silent mating type information regulation 2 homolog) 2 (S.cerevisiae), SIRT2_HUMAN, SIRT 2, SIR2-like protein 2, SIR2L2, SIR2L, SIR2, S. cerevisiae, homolog-loke 2, Sir2 related protein type 2, SIR2 like protein 2, SIR2, Silent information regulator 2, Silencing information regulator 2 like, Regulatory protein SIR2 homolog 2, NAD-dependent protein deacetylase sirtuin-2, NAD-dependent deacetylase sirtuin-2, NAD dependent deacetylase sirtuin 2, FLJ37491, FLJ35621
Anti-SIRT2 Antibody (2G702) 是一种 Rabbit 抗体，靶向 SIRT2。Anti-SIRT2 Antibody (2G702) 可用于 ICC/IF,IP,FCM。
Anti-SIRT2 Antibody (2G702)
Anti-SIRT2 Antibody (2G702)
还可以产品编号 TMAC-03762 别名 Sirtuin type 2, Sirtuin 2, Sirtuin (silent mating type information regulation 2 homolog) 2 (S.cerevisiae), SIRT2_HUMAN, SIRT 2, SIR2-like protein 2, SIR2L2, SIR2L, SIR2, S. cerevisiae, homolog-loke 2, Sir2 related protein type 2, SIR2 like protein 2, SIR2, Silent information regulator 2, Silencing information regulator 2 like, Regulatory protein SIR2 homolog 2, NAD-dependent protein deacetylase sirtuin-2, NAD-dependent deacetylase sirtuin-2, NAD dependent deacetylase sirtuin 2, FLJ37491, FLJ35621
Anti-SIRT2 Antibody (2G702) 是一种 Rabbit 抗体，靶向 SIRT2。Anti-SIRT2 Antibody (2G702) 可用于 ICC/IF,IP,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,495 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
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| 产品描述 | Anti-SIRT2 Antibody (2G702) is a Rabbit antibody targeting SIRT2. Anti-SIRT2 Antibody (2G702) can be used in ICC/IF,IP,FCM. |
| 别名 | Sirtuin type 2, Sirtuin 2, Sirtuin (silent mating type information regulation 2 homolog) 2 (S.cerevisiae), SIRT2_HUMAN, SIRT 2, SIR2-like protein 2, SIR2L2, SIR2L, SIR2, S. cerevisiae, homolog-loke 2, Sir2 related protein type 2, SIR2 like protein 2, SIR2, Silent information regulator 2, Silencing information regulator 2 like, Regulatory protein SIR2 homolog 2, NAD-dependent protein deacetylase sirtuin-2, NAD-dependent deacetylase sirtuin-2, NAD dependent deacetylase sirtuin 2, FLJ37491, FLJ35621 |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. ICC staining SIRT2 in 293 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 2. ICC staining SIRT2 in PC-12 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. Flow cytometric analysis of Hela cells with SIRT2 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. |
| 应用 | |
| 推荐剂量 | ICC/IF: 1:50-200; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | The silent information regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and are involved in diverse processes, including transcriptional regulation, cell cycle progression, DNA-damage repair and aging. In S. cerevisiae, Sir2p deacetylates histones in a NAD-dependent manner, which regulates silencing at the telomeric, rDNA and silent mating-type loci. Sir2p is the founding member of a large family, designated sirtuins, which contain a conserved catalytic domain. The human homologs, which include SIRT1-7, are divided into four main branches: SIRT1-3 are class I, SIRT4 is class II, SIRT5 is class III and SIRT6-7 are class IV. SIRT proteins may function via mono-ADP-ribosylation of proteins. SIRT2 contains a 323 amino acid catalytic core domain with a NAD-binding domain and a large groove which is the likely site of catalysis. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 43 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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