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顶部生物活性储存和溶解信息计算器

Anti-Phospho-PRKAA2 (Ser345) Antibody (4R913)

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Anti-Phospho-PRKAA2 (Ser345) Antibody (4R913)
产品编号 TMAC-03191
别名 Protein kinase AMP activated catalytic subunit alpha 2, Protein kinase AMP activated alpha 2 catalytic subunit, PRKAA2, PRKAA, p-AMPK alpha 2 (Ser345), p-AMPK alpha 2 (S345), Hydroxymethylglutaryl-CoA reductase kinase, HMGCR kinase, AMPK-a2AMPKalpha2, AMPKa2, AMPK2, AMPK subunit alpha-2, AMPK alpha 2 chain, AMPK alpha 2 (p-Ser345), AMPK alpha 2 (p-S345), AMPK a2, AMPK 2, Acetyl-CoA carboxylase kinase, ACACA kinase, AAPK2, AAPK1, 5'-AMP-activated protein kinase catalytic subunit alpha-2

Anti-Phospho-PRKAA2 (S345) Antibody (4R913) 是一种 Rabbit 抗体，靶向 Phospho-PRKAA2 (S345)。Anti-Phospho-PRKAA2 (S345) Antibody (4R913) 可用于 WB,ICC/IF,IHC。

Anti-Phospho-PRKAA2 (Ser345) Antibody (4R913)

Anti-Phospho-PRKAA2 (Ser345) Antibody (4R913)

Rating icon 还可以
Anti-Phospho-PRKAA2 (Ser345) Antibody (4R913)
产品编号 TMAC-03191 别名 Protein kinase AMP activated catalytic subunit alpha 2, Protein kinase AMP activated alpha 2 catalytic subunit, PRKAA2, PRKAA, p-AMPK alpha 2 (Ser345), p-AMPK alpha 2 (S345), Hydroxymethylglutaryl-CoA reductase kinase, HMGCR kinase, AMPK-a2AMPKalpha2, AMPKa2, AMPK2, AMPK subunit alpha-2, AMPK alpha 2 chain, AMPK alpha 2 (p-Ser345), AMPK alpha 2 (p-S345), AMPK a2, AMPK 2, Acetyl-CoA carboxylase kinase, ACACA kinase, AAPK2, AAPK1, 5'-AMP-activated protein kinase catalytic subunit alpha-2

Anti-Phospho-PRKAA2 (S345) Antibody (4R913) 是一种 Rabbit 抗体，靶向 Phospho-PRKAA2 (S345)。Anti-Phospho-PRKAA2 (S345) Antibody (4R913) 可用于 WB,ICC/IF,IHC。

规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-PRKAA2 (Ser345) Antibody (4R913) 是一种 Rabbit 抗体，靶向 Phospho-PRKAA2 (Ser345)。Anti-Phospho-PRKAA2 (Ser345) Antibody (4R913) 可用于 WB,ICC/IF,IHC。
别名Protein kinase AMP activated catalytic subunit alpha 2, Protein kinase AMP activated alpha 2 catalytic subunit, PRKAA2, PRKAA, p-AMPK alpha 2 (Ser345), p-AMPK alpha 2 (S345), Hydroxymethylglutaryl-CoA reductase kinase, HMGCR kinase, AMPK-a2AMPKalpha2, AMPKa2, AMPK2, AMPK subunit alpha-2, AMPK alpha 2 chain, AMPK alpha 2 (p-Ser345), AMPK alpha 2 (p-S345), AMPK a2, AMPK 2, Acetyl-CoA carboxylase kinase, ACACA kinase, AAPK2, AAPK1, 5'-AMP-activated protein kinase catalytic subunit alpha-2
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-Phospho-AMPK alpha 2 (S345) antibody. Counter stained with hematoxylin.
2. Immunohistochemical analysis of paraffin-embedded mouse pancreas tissue using anti-Phospho-AMPK alpha 2 (S345) antibody. Counter stained with hematoxylin.
3. ICC staining Phospho-AMPK alpha 2 (S345) in 293 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. ICC staining Phospho-AMPK alpha 2 (S345) in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
应用
WB
ICC/IF
IHC
推荐剂量
WB: 1:500-1000; IHC: 1:50-100; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Five-prime-AMP-activated protein kinase, known as AMPK, is a heterotrimeric complex that comprises of a catalytic α subunit, and regulatory β and γ. AMPK protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK is activated by high AMP and low ATP via a mechanism involving allosteric regulation, promotion of phosphorylation by an upstream protein kinase known as AMPK kinase (AMPKK), and inhibition of dephosphorylation. Activated AMPK can phosphorylate and regulate in vivo hydroxymethylglutaryl-CoA reductase and acetyl-CoA carboxylase, which are key regulatory enzymes of sterol synthesis and fatty acid synthesis, respectively. The human AMPKα1 gene maps to chromosome 5p12 and encodes a 548 amino acid protein. The major regulatory site phosphorylated by AMPKK on AMPKα has been identified as Thr 172 within the activation loop between the DFG and APE motifs of the alpha-subunits.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
A synthesized phosphopeptide: human AMPK alpha 2 around the phosphorylation site of Ser345
抗原种属
human
Uniprot ID
P54646
化学信息
分子量Theoretical: 62 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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关键词

pAMPK alpha 2 (Ser345)pAMPK alpha 2 (S345)AMPK alpha 2 (pSer345)AMPK alpha 2 (pS345)AMPK alpha 2 (phospho-Ser345)AMPK alpha 2 (phospho-S345)

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4个月前
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