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Anti-PLA2G1B Antibody (8U699) 是一种 Rabbit 抗体,靶向 PLA2G1B。Anti-PLA2G1B Antibody (8U699) 可用于 ELISA。
Anti-PLA2G1B Antibody (8U699) 是一种 Rabbit 抗体,靶向 PLA2G1B。Anti-PLA2G1B Antibody (8U699) 可用于 ELISA。
产品描述 | Anti-PLA2G1B Antibody (8U699) is a Rabbit antibody targeting PLA2G1B. Anti-PLA2G1B Antibody (8U699) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 8U699 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human PLA2G1B (rh PLA2G1B; TMPY-01689; NP_000919.1; Met1-Ser148). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | phospholipase A2, also known as Phosphatidylcholine 2-acylhydrolase 1B, Group IB phospholipase A2, PLA2 and PLA2G1B, is a secreted protein that belongs to the phospholipase A2 family. Phospholipase A2 / PLA2G1B catalyzes the release of fatty acids from glycero-3-phosphocholines. The best known varieties are the digestive enzymes secreted as zymogens by the pancreas of mammals. Sequences of pancreatic Phospholipase A2 / PLA2G1B enzymes from a variety of mammals have been reported. One striking feature of these enzymes is their close homology to venom phospholipases of snakes. Other forms of Phospholipase A2 / PLA2G1B have been isolated from brain, liver, lung, spleen, intestine, macrophages, leukocytes, erythrocytes, inflammatory exudates, chondrocytes, and platelets. Mice lacking in Phospholipase A2 / PLA2G1B are resistant to obesity and diabetes induced by feeding a diabetogenic high-fat/high-carbohydrate diet. Oral supplementation of a diabetogenic diet with the PLA2G1B inhibitor methyl indoxam effectively suppresses diet-induced obesity and diabetes. PLA2G1B inhibition may be a potentially effective oral therapeutic option for treatment of obesity and diabetes. |
偶联 | Unconjugated |
免疫原 | Recombinant Human PLA2G1B Protein (TMPY-01689) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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