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Anti-PP2A alpha/beta Antibody (6N831)

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Anti-PP2A alpha/beta Antibody (6N831)
产品编号 TMAC-03393
别名 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, Serine/threonine protein phosphatase 2A catalytic subunit beta isoform, Serine/threonine protein phosphatase 2A catalytic subunit alpha isoform, RP-C, RP C, Replication protein C, Protein phosphatase 2 catalytic subunit beta isoform, Protein phosphatase 2 catalytic subunit alpha isoform, PPP2CB, PPP2CA, PP2CB, PP2Aα/β, PP2Ac, PP2Aalpha/beta, PP2A-alpha, PP2AA_HUMAN, PP2Aa/b, PP2A α/β, PP2A beta, PP2A B, PP2A alpha, PP2A a/b, PP2A A

Anti-PP2A alpha/beta Antibody (6N831) 是一种 Rabbit 抗体,靶向 PP2A alpha/beta。Anti-PP2A alpha/beta Antibody (6N831) 可用于 WB,ICC,IHC,IP。

Anti-PP2A alpha/beta Antibody (6N831)

Anti-PP2A alpha/beta Antibody (6N831)

Rating icon 还可以
Anti-PP2A alpha/beta Antibody (6N831)
产品编号 TMAC-03393 别名 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, Serine/threonine protein phosphatase 2A catalytic subunit beta isoform, Serine/threonine protein phosphatase 2A catalytic subunit alpha isoform, RP-C, RP C, Replication protein C, Protein phosphatase 2 catalytic subunit beta isoform, Protein phosphatase 2 catalytic subunit alpha isoform, PPP2CB, PPP2CA, PP2CB, PP2Aα/β, PP2Ac, PP2Aalpha/beta, PP2A-alpha, PP2AA_HUMAN, PP2Aa/b, PP2A α/β, PP2A beta, PP2A B, PP2A alpha, PP2A a/b, PP2A A

Anti-PP2A alpha/beta Antibody (6N831) 是一种 Rabbit 抗体,靶向 PP2A alpha/beta。Anti-PP2A alpha/beta Antibody (6N831) 可用于 WB,ICC,IHC,IP。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-PP2A alpha/beta Antibody (6N831) is a Rabbit antibody targeting PP2A alpha/beta. Anti-PP2A alpha/beta Antibody (6N831) can be used in WB,ICC,IHC,IP.
别名Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, Serine/threonine protein phosphatase 2A catalytic subunit beta isoform, Serine/threonine protein phosphatase 2A catalytic subunit alpha isoform, RP-C, RP C, Replication protein C, Protein phosphatase 2 catalytic subunit beta isoform, Protein phosphatase 2 catalytic subunit alpha isoform, PPP2CB, PPP2CA, PP2CB, PP2Aα/β, PP2Ac, PP2Aalpha/beta, PP2A-alpha, PP2AA_HUMAN, PP2Aa/b, PP2A α/β, PP2A beta, PP2A B, PP2A alpha, PP2A a/b, PP2A A
Ig Type
IgG
交叉反应
Human,Mouse,Rat,zebrafish
验证活性
1. Western blot analysis of PP2A alpha + beta on different lysates using anti-PP2A alpha + beta antibody at 1/1,000 dilution. Positive control: Lane 1: A431, Lane 2: NIH/3T3, Lane 3: 293T.
2. Western blot analysis of PP2A alpha + beta on hybrid fish (crucian-carp) brain tissue lysate using anti-PP2A alpha + beta antibody at 1/500 dilution.
3. Immunohistochemical analysis of paraffin-embedded mouse stomach tissue using anti-PP2A alpha + beta antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded mouse heart tissue using anti-PP2A alpha + beta antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded rat kidney tissue using anti-PP2A alpha + beta antibody. Counter stained with hematoxylin.
6. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-PP2A alpha + beta antibody. Counter stained with hematoxylin.


7. Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-PP2A alpha + beta antibody. Counter stained with hematoxylin.
8. Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-PP2A alpha + beta antibody. Counter stained with hematoxylin.
9. ICC staining PP2A alpha + beta in PANC-1 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
10. ICC staining PP2A alpha + beta in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
11. ICC staining PP2A alpha + beta in 293 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
12. ICC staining PP2A alpha + beta in L6 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

应用
推荐剂量
WB: 1:1000-2000; IHC: 1:100-200; ICC: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The catalytic subunit of protein phosphatase 2A (PP2A) is inactivated by in vitro phosphorylation of Tyr-307 by receptor and nonreceptor protein tyrosine kinases. The catalytic subunit of PP2A is phosphorylated by tyrosine-specific protein kinases and associates with a variety of regulatory subunits. Phosphorylation is enhanced in the presence of the phosphatase inhibitor okadaic acid, consistent with an autodephosphorylation reaction. Phosphorylation is catalyzed by p60v-src, p56lck, epidermal growth factor receptors, and insulin receptors. Transient deactivation of PP2A might enhance transmission of cellular signals through kinase cascades within cells. In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
化学信息
分子量Theoretical: 36 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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