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Anti-PP2A alpha/beta Antibody (6N831) 是一种 Rabbit 抗体,靶向 PP2A alpha/beta。Anti-PP2A alpha/beta Antibody (6N831) 可用于 WB,ICC,IHC,IP。
Anti-PP2A alpha/beta Antibody (6N831) 是一种 Rabbit 抗体,靶向 PP2A alpha/beta。Anti-PP2A alpha/beta Antibody (6N831) 可用于 WB,ICC,IHC,IP。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,490 | 5日内发货 | |
100 μL | ¥ 2,495 | 5日内发货 |
产品描述 | Anti-PP2A alpha/beta Antibody (6N831) is a Rabbit antibody targeting PP2A alpha/beta. Anti-PP2A alpha/beta Antibody (6N831) can be used in WB,ICC,IHC,IP. |
别名 | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, Serine/threonine protein phosphatase 2A catalytic subunit beta isoform, Serine/threonine protein phosphatase 2A catalytic subunit alpha isoform, RP-C, RP C, Replication protein C, Protein phosphatase 2 catalytic subunit beta isoform, Protein phosphatase 2 catalytic subunit alpha isoform, PPP2CB, PPP2CA, PP2CB, PP2Aα/β, PP2Ac, PP2Aalpha/beta, PP2A-alpha, PP2AA_HUMAN, PP2Aa/b, PP2A α/β, PP2A beta, PP2A B, PP2A alpha, PP2A a/b, PP2A A |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat,zebrafish |
验证活性 | 1. Western blot analysis of PP2A alpha + beta on different lysates using anti-PP2A alpha + beta antibody at 1/1,000 dilution. Positive control: Lane 1: A431, Lane 2: NIH/3T3, Lane 3: 293T. 2. Western blot analysis of PP2A alpha + beta on hybrid fish (crucian-carp) brain tissue lysate using anti-PP2A alpha + beta antibody at 1/500 dilution. 3. Immunohistochemical analysis of paraffin-embedded mouse stomach tissue using anti-PP2A alpha + beta antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse heart tissue using anti-PP2A alpha + beta antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded rat kidney tissue using anti-PP2A alpha + beta antibody. Counter stained with hematoxylin. 6. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-PP2A alpha + beta antibody. Counter stained with hematoxylin. |
应用 | |
推荐剂量 | WB: 1:1000-2000; IHC: 1:100-200; ICC: 1:50-200 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | The catalytic subunit of protein phosphatase 2A (PP2A) is inactivated by in vitro phosphorylation of Tyr-307 by receptor and nonreceptor protein tyrosine kinases. The catalytic subunit of PP2A is phosphorylated by tyrosine-specific protein kinases and associates with a variety of regulatory subunits. Phosphorylation is enhanced in the presence of the phosphatase inhibitor okadaic acid, consistent with an autodephosphorylation reaction. Phosphorylation is catalyzed by p60v-src, p56lck, epidermal growth factor receptors, and insulin receptors. Transient deactivation of PP2A might enhance transmission of cellular signals through kinase cascades within cells. In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
分子量 | Theoretical: 36 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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