CD40 Protein, Human, Recombinant (His & Avi), Biotinylated

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SPR兼容缓冲液

产品编号 TMPY-05614

CD40 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 22.4 kDa and the accession number is A0A0S2Z3C7.

CD40 Protein, Human, Recombinant (His & Avi), Biotinylated

一键复制产品信息

SPR兼容缓冲液

产品编号 TMPY-05614

规格	价格	库存
5 μg	¥ 987	6-8日内发货
10 μg	¥ 1,700	6-8日内发货
20 μg	¥ 2,940	5日内发货
50 μg	¥ 4,730	5日内发货
100 μg	¥ 7,880	5日内发货

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产品信息

生物活性	Immobilized Human CD40 Protein (ECD, His & AVI Tag), Biotinylated at 2 μg/mL (100 μL/well) can bind Human CD40 Ligand Protein (ECD, hFc Tag) , the EC50 is 6-40 ng/mL.
产品描述	CD40 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 22.4 kDa and the accession number is A0A0S2Z3C7.
种属	Human
表达系统	HEK293 Cells
标签	His, Avi
蛋白编号	P25942
别名	TNFRSF5,p50,CDW40,CD40 molecule, TNF receptor superfamily member 5,Bp50
蛋白构建	A DNA sequence encoding the human CD40 (NP_001241.1) (Met1-Arg193) was expressed with a c-terminal polyhistidine tagged AVI tag at the C-terminus. The expressed protein was biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed. Predicted N terminal: Glu 21
蛋白纯度	> 95 % as determined by SDS-PAGE.
分子量	22.4 kDa (predicted)
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 protein is expressed in B cells, dendritic cells, macrophages, endothelial cells, and several tumor cell lines. Defects in CD40 result in hyper-IgM immunodeficiency type 3 (HIGM3). In addition, CD40/CD40L interaction is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy