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RBP4 Protein, Human, Recombinant (Tris-HCl, His)

产品编号 TMPS-00122

RBP4 Protein, Human, Recombinant (Tris-HCl, His) is expressed in HEK293 Cells. The accession number is P02753.

RBP4 Protein, Human, Recombinant (Tris-HCl, His)

产品编号 TMPS-00122

RBP4 Protein, Human, Recombinant (Tris-HCl, His) is expressed in HEK293 Cells. The accession number is P02753.

规格	价格	库存	数量
10 μg	¥ 863	5日内发货
50 μg	¥ 2,300	5日内发货

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产品信息

生物活性	Measured by its ability to bind all-trans retinoic acid. The binding of retinoic acid results in the quenching of Trp fluorescence in RBP4. > 1.0 µM all-trans retinoic acid is bound under the described conditions.
产品描述	RBP4 Protein, Human, Recombinant (Tris-HCl, His) is expressed in HEK293 Cells. The accession number is P02753.
种属	Human
表达系统	HEK293 Cells
标签	His
蛋白编号	P02753
别名	Retinol-Binding Protein 4,RBP-4
蛋白构建	Glu19-Leu201
蛋白纯度	> 97% as determined by SDS-PAGE; > 97% as determined by HPLC
分子量	~22 kDa (Reducing conditions)
内毒素	< 0.2 EU/μg of protein as determined by the LAL method.
缓冲液	Lyophilized from a 0.2 μm filtered solution in 50 mM Tris-HCl, 150 mM NaCl, pH 7.5.
复溶方法	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	The properties of retinol binding protein is the transport carrier of vitamin A in the plasma. Human-retinol binding protein is a single-chain polypeptide with a molecular weight of approximately 21000 and one binding site for retinol and other forms of vitamin A. In addition, compounds related to retinol, such as retinal, retinoic acid, retinyl esters and geometric isomers of retinol and of retinal were evaluated for their ability to bind to this protein. In plasma, RBP4-retinol forms a complex with transthyretin (TTR), also known as thyroxine-binding protein and prealbumin. Defects in RBP4 cause retinol-binding protein deficiency, which affects night vision.