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Anti-ABCB11 Antibody (1N110)

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货号 TMAB-02144

Anti-ABCB11 Antibody (1N110) 是一种 Rabbit 抗体，靶向 ABCB11。Anti-ABCB11 Antibody (1N110) 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-ABCB11 Antibody (1N110)

Anti-ABCB11 Antibody (1N110)

一键复制产品信息
Rating icon 还可以
货号 TMAB-02144

Anti-ABCB11 Antibody (1N110) 是一种 Rabbit 抗体，靶向 ABCB11。Anti-ABCB11 Antibody (1N110) 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-ABCB11 Antibody (1N110) is a Rabbit antibody targeting ABCB11. Anti-ABCB11 Antibody (1N110) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
1N110
反应种属
Human (predicted:Mouse)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-1000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Membrane; Multi-pass membrane protein.
组织特异性Expressed predominantly, if not exclusively in the liver, where it was further localized to the canalicular microvilli and to subcanalicular vesicles of the hepatocytes by in situ.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. [provided by RefSeq, Jul 2008]
抗原信息
基因名称
ABCB11
基因ID
8647
蛋白名称
Bile salt export pump
功能
Involved in the ATP-dependent secretion of bile salts into the canaliculus of hepatocytes.
化学信息
分子量Theoretical: 146 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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