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Anti-SSTR2 Antibody (8O74)
还可以产品编号 TMAH-01134
别名 somatostatin receptor 2
Anti-SSTR2 Antibody (8O74) 是一种抗体，靶向 SSTR2。Anti-SSTR2 Antibody (8O74) 可用于 ELISA,FC。
Anti-SSTR2 Antibody (8O74)
Anti-SSTR2 Antibody (8O74)
还可以产品编号 TMAH-01134 别名 somatostatin receptor 2
Anti-SSTR2 Antibody (8O74) 是一种抗体，靶向 SSTR2。Anti-SSTR2 Antibody (8O74) 可用于 ELISA,FC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,315 | 5日内发货 | |
| 100 μL | ¥ 2,195 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-SSTR2 Antibody (8O74) is an antibody targeting SSTR2. Anti-SSTR2 Antibody (8O74) can be used in ELISA,FC. |
| 别名 | somatostatin receptor 2 |
| Ig Type | Human IgG1 |
| 克隆号 | 8O74 |
| 交叉反应 | Human |
| 验证活性 | 1. Untransfected CT26 cells surface (green line) and transfected Human SSTR2 CT26 stable cells surface (red line) were stained with anti-SSTR2 recombinant antibody (2µg/1*10^6 cells), washed and then followed by APC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry. 2. The Binding Activity of Huamn SSTR2 with Anti-SSTR2 recombinant Antibody Activity: Measured by its binding ability in a functional ELISA. Immobilized Human SSTR2 at 10 μg/mL can bind Anti-SSTR2 recombinant antibody (TMAH-01134), the EC50 is 58.13-81.28 ng/mL. |
| 应用 | ELISA, FC |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. Cytoplasm. Note=Located mainly at the cell surface under basal conditions. Agonist stimulation results in internalization to the cytoplasm. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| 研究背景 | Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human SSTR2 Protein |
| 抗原种属 | Human |
| 基因ID | 6752 |
| Uniprot ID | |
| 研究领域 | Immunology |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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