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Anti-Neuroligin 1 Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 Neuroligin 1。Anti-Neuroligin 1 Polyclonal Antibody 2 可用于 WB。
Anti-Neuroligin 1 Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 Neuroligin 1。Anti-Neuroligin 1 Polyclonal Antibody 2 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-Neuroligin 1 Polyclonal Antibody 2 is a Rabbit antibody targeting Neuroligin 1. Anti-Neuroligin 1 Polyclonal Antibody 2 can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Human,Mouse (predicted:Chicken,Dog,Pig,Cow,Horse,Sheep) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cell membrane; Single-pass type I membrane protein. Cell junction, synapse. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Note=Enriched in synaptic plasma membranes and clustered in synaptic clefts and postsynaptic densities. Detected at dendritic spines. Colocalized with DLG4/PSD-95 and GRIN1/NMDAR1. |
| 组织特异性 | Expressed in the blood vessel walls (at protein level). Detected in brain, and at lower levels in pancreas islet beta cells. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Neuroligin 1 is a synaptic cell-adhesion molecule that is enriched in postsynaptic densities where it may recruit receptors, channels, and signal-transduction molecules to synaptic sites of cell adhesion. In addition, the neuroligin/beta-neurexin junction may be involved in the excitatory/inhibitory specification of CNS neuron synapses. A role for Neuroligin 1 is also suggested in autism. |
| 免疫原 | KLH conjugated synthetic peptide: human Neuroligin 1 |
| 抗原种属 | Human |
| 基因名称 | NLGN1 |
| 基因ID | |
| 蛋白名称 | Neuroligin-1 |
| Uniprot ID | |
| 功能 | Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses. |
| 分子量 | Theoretical: 87 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |