CD93/C1qR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 85.2 kDa and the accession number is Q9NPY3.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
50 μg | ¥ 3,170 | 5日内发货 | ||
500 μg | ¥ 20,800 | 5日内发货 |
生物活性 | Immobilized Human IGFBP7 (His Tag) at 2 μg/ml (100 μl/well) can bind Human CD93 (hFc Tag). The EC50 is 15-120 ng/ml. |
产品描述 | CD93/C1qR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 85.2 kDa and the accession number is Q9NPY3. |
种属 | Human |
表达系统 | HEK293 Cells |
标签 | C-hFc |
蛋白编号 | Q9NPY3 |
别名 | C1QR1, dJ737E23.1, C1qRP, C1qR, MXRA4, C1qR(P), ECSM3, CD93 molecule, CDw93 |
蛋白构建 | The Human CD93 (Q9NPY3) extracellular domain (Met 1-Lys 580) was fused with the Fc region of Human IgG1 at the C-terminus. |
蛋白纯度 | > 85 % as determined by SDS-PAGE |
分子量 | 85.2 kDa (predicted) |
内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
存储 |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. |
研究背景 | CD93 or C1q receptor 1 (C1qR) is an about 120 kDa O-sialoglycoprotein that within the hematopoietic system is selectively expressed on cells of the myeloid lineage. CD93/C1qR is a highly glycosylated transmembrane protein expressed on monocytes, neutrophils, endothelial cells, and stem cells. CD93 was originally identified as a myeloid cell-surface marker and subsequently associated with an ability to modulate phagocytosis of suboptimally opsonized immunoglobulin G and complement particles in vitro. CD93/C1qR, a receptor expressed during early B-cell development, is reinduced during plasma-cell differentiation. High CD93/CD138 expression was restricted to antibody-secreting cells both in T-dependent and T-independent responses as naive, memory, and germinal-center B cells remained CD93-negative. CD93 was expressed on (pre)plasmablasts/plasma cells, including long-lived plasma cells that showed decreased cell cycle activity, high levels of isotype-switched Ig secretion, and modification of the transcriptional network. CD93 is important for the maintenance of plasma cells in bone marrow niches. |
bottom
您可能有的问题的答案可以在重组蛋白操作手册中找到
CD93/C1qR1 Protein, Human, Recombinant (hFc) C1QR1 ECSM-3 dJ737E23.1 MXRA-4 C1qRP ECSM 3 C1qR MXRA4 C1qR(P) ECSM3 CD93 molecule CDw93 MXRA 4 recombinant recombinant-proteins proteins protein