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Anti-ACRV1 Antibody (4E707) 是一种 Mouse 抗体,靶向 ACRV1。Anti-ACRV1 Antibody (4E707) 可用于 ELISA(Cap)。
Anti-ACRV1 Antibody (4E707) 是一种 Mouse 抗体,靶向 ACRV1。Anti-ACRV1 Antibody (4E707) 可用于 ELISA(Cap)。
产品描述 | Anti-ACRV1 Antibody (4E707) is a Mouse antibody targeting ACRV1. Anti-ACRV1 Antibody (4E707) can be used in ELISA(Cap). |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 4E707 |
交叉反应 | Human |
应用 | ELISA(Cap) |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human ACRV1 (rh ACRV1; TMPY-01813; P26436-1; Gln22-Ile265). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Acrosomal protein SP-1, also known as Acrosomal vesicle protein 1 and ACRV1, is a testis-specific, differentiation antigen, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. Regulation of cell type-specific gene transcription is central to cellular differentiation and development. During spermatogenesis, a number of testis-specific genes are expressed in a precise spatiotemporal order. The longest transcript of ACRV1 / SP-1 is the most abundant, comprising 53-72% of the total acrosomal vesicle protein 1 messages; the second largest transcript comprises 15-32%; the third and the fourth largest transcripts account for 3.4-8.3% and 8.7-12.5%, respectively; and the remaining transcripts combined account for < 1% of the total acrosomal vesicle protein 1 message. ACRV1 / SP-1 is a testis-specific acrosomal protein that has been detected in several species including humans. It may be involved in sperm-zona binding or penetration, and it is a potential contraceptive vaccine immunogen for humans. ACRV1 / SP-1 may be involved in sperm-zona binding or penetration. It is also a intra-acrosomal protein that is considered to be a vaccine candidate for immunocontraception. |
偶联 | Unconjugated |
免疫原 | Recombinant Human ACRV1 Protein (TMPY-01813) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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