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Anti-human CD34 Antibody (3W683)

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货号 TMAB-07404

Anti-human CD34 Antibody (3W683) 是一种 Mouse 抗体，靶向 human CD34。Anti-human CD34 Antibody (3W683) 可用于 FCM。

Anti-human CD34 Antibody (3W683)

Anti-human CD34 Antibody (3W683)

一键复制产品信息
Rating icon 还可以
货号 TMAB-07404

Anti-human CD34 Antibody (3W683) 是一种 Mouse 抗体，靶向 human CD34。Anti-human CD34 Antibody (3W683) 可用于 FCM。

规格价格库存数量
100 μg
¥ 1,870
5日内发货
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产品介绍

生物活性
产品描述
Anti-human CD34 Antibody (3W683) is a Mouse antibody targeting human CD34. Anti-human CD34 Antibody (3W683) can be used in FCM.
Ig Type
Mouse IgG1
克隆号
3W683
反应种属
Human
应用FCM
推荐剂量
FCM: 0.5μg/Test
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Membrane; Single-pass type I membrane protein.
组织特异性Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4).
浓度1mg/ml
研究背景The highly glycosylated 75-120 kD antigen CD34 is possibly an adhesion molecule with a putative role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. It could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. CD34 is thought to have a role in presenting carbohydrate ligands to selectins. The intracellular chain of the CD34 antigen is a site of phosphorylation by activated protein kinase C, suggesting a putative role in signal transduction. Two isoforms of CD34 have been reported to be generated by alternative splicing. CD34 is highly expressed on hematopoietic progenitors, as well as on endothelial cells, brain, and testis. Staining for CD34 has been used to measure angiogenesis, which reportedly predicts tumor recurrence.
抗原信息
免疫原
KLH conjugated synthetic peptide: human CD34
抗原种属
Human
基因名称
CD34
基因ID
947
蛋白名称
Hematopoietic progenitor cell antigen CD34
Uniprot ID
P28906
功能
Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.
化学信息
分子量Theoretical: 39 kDa. Actual: 105-120 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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