购物车
- 全部删除
您的购物车当前为空
Anti-TrkB Antibody (1F424)
还可以产品编号 TMAY-00169
Anti-TrkB Antibody (1F424) 是一种 Rabbit 抗体，靶向 TrkB。Anti-TrkB Antibody (1F424) 可用于 ELISA。
Anti-TrkB Antibody (1F424)
Anti-TrkB Antibody (1F424)
还可以产品编号 TMAY-00169
Anti-TrkB Antibody (1F424) 是一种 Rabbit 抗体，靶向 TrkB。Anti-TrkB Antibody (1F424) 可用于 ELISA。
产品信息正在更新中，如果您想购买，请点击大包装&定制按钮.
大包装 & 定制
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-TrkB Antibody (1F424) is a Rabbit antibody targeting TrkB. Anti-TrkB Antibody (1F424) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 1F424 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human NTRK2 / Trk-B extracellular domain (rh Trk-B; TMPY-00751; NP_001007098.1; Met 1-His 430). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | TrkB receptor also known as TrkB tyrosine kinase or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase, receptor, type 2 (NTRK2) is a single transmembrane catalytic receptor with intracellular tyrosine kinase activity. TrkB/NTRK2 is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. TrkB tyrosine kinase (TrkB) or NTRK2 is coupled to the Ras, Cdc42/Rac/RhoG, MAPK, PI3-K, and PLCgamma signaling pathways. There are four members of the Trk family; TrkA, TrkB, and TrkC and a related p75NTR receptor. Each family member binds different neurotrophins with varying affinities. TrkB/NTRK has the highest affinity for brain-derived neurotrophic factor (BDNF) and is involved in neuronal plasticity, long-term potentiation, and apoptosis of CNS neurons. Other neurotrophins includenerve growth factor(NGF), neurotrophin-3 and neurotrophin-4. TrkB/NTRK is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signaling through this kinase leads to cell differentiation. Mutations in TrkB/NTRK have been associated with obesity and mood disorders.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human Trk-B protein (TMPY-00751) |
| 抗原种属 | Human |
| 研究领域 | Receptor Tyrosine Kinases (RTKs), Cancer Drug Targets |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
评论列表
预览
Related Tags: buy Anti-TrkB Antibody (1F424) | purchase Anti-TrkB Antibody (1F424) | Anti-TrkB Antibody (1F424) cost | order Anti-TrkB Antibody (1F424)
嗨！有任何问题？点我咨询
评论内容