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Anti-TNF-alpha Antibody (3M493) 是一种 Mouse 抗体,靶向 TNF-alpha。Anti-TNF-alpha Antibody (3M493) 可用于 ELISA。
Anti-TNF-alpha Antibody (3M493) 是一种 Mouse 抗体,靶向 TNF-alpha。Anti-TNF-alpha Antibody (3M493) 可用于 ELISA。
产品描述 | Anti-TNF-alpha Antibody (3M493) is a Mouse antibody targeting TNF-alpha. Anti-TNF-alpha Antibody (3M493) can be used in ELISA. |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 3M493 |
交叉反应 | Canine |
应用 | ELISA |
推荐剂量 | ELISA: 0.5-1 μg/mL |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Canine TNF-alpha (rCanine TNF-alpha; Catalog #70003-DNAE; NP_001003244.4; Val 77-Leu 233). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS with 5% trehalose |
研究背景 | Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Two receptors, TNF-R1 (TNF receptor type 1; CD120a; p55/60) and TNF-R2 (TNF receptor type 2; CD120b; p75/80), bind to TNF-alpha. TNF-alpha protein is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). TNF-alpha is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment.TNF-alpha Protein & AntibodyCancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
偶联 | Unconjugated |
免疫原 | Recombinant Canine TNF-alpha Protein (TMPY-01594) |
抗原种属 | Canine |
研究领域 | Cancer Drug Targets, Neuroinflammation |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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