Anti-Pellino 2 Polyclonal Antibody is a Rabbit antibody targeting Pellino 2. Anti-Pellino 2 Polyclonal Antibody can be used in WB.

IgG

Mouse (predicted:Human,Chicken,Pig,Cow,Horse,Sheep)

WB: 1:500-2000

Polyclonal

KLH conjugated synthetic peptide: human Pellino 2

Human

PELI2

E3 ubiquitin-protein ligase pellino homolog 2

E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates IL1B-induced IRAK1 'Lys-63'-linked polyubiquitination and possibly 'Lys-48'-linked ubiquitination. May be important for LPS- and IL1B-induced MAP3K7-dependent, but not MAP3K3-dependent, NF-kappa-B activation. Can activate the MAP (mitogen activated protein) kinase pathway leading to activation of ELK1.