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Anti-Phospho-FBXL3 (Ser320) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-FBXL3 (Ser320)。Anti-Phospho-FBXL3 (Ser320) Polyclonal Antibody 可用于 WB。
Anti-Phospho-FBXL3 (Ser320) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-FBXL3 (Ser320)。Anti-Phospho-FBXL3 (Ser320) Polyclonal Antibody 可用于 WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,235 | 5日内发货 |
产品描述 | Anti-Phospho-FBXL3 (Ser320) Polyclonal Antibody is a Rabbit antibody targeting Phospho-FBXL3 (Ser320). Anti-Phospho-FBXL3 (Ser320) Polyclonal Antibody can be used in WB. |
别名 | p-FBXL3 (Ser320), p-FBXL3 (S320), FBXL3 (p-Ser320), FBXL3 (p-S320) |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of extracts from Hela cells treated with TNFa (lane 2) and mouse brain tissus (lane 1) using FBXL3 (Phospho-Ser320) Antibody TMAC-01452. |
应用 | |
推荐剂量 | WB: 1:500-1000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
性状 | Liquid |
缓冲液 | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | Substrate-recognition component of the SCF(FBXL3) E3 ubiquitin ligase complex involved in circadian rhythm function. Plays a key role in the maintenance of both the speed and the robustness of the circadian clock oscillation. The SCF(FBXL3) complex mainly acts in the nucleus and mediates ubiquitination and subsequent degradation of CRY1 and CRY2. Activity of the SCF(FBXL3) complex is counteracted by the SCF(FBXL21) complex. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | Peptide sequence around phosphorylation site of serine 320 (S-V-S(p)-K-D) derived from Human FBXL3 |
抗原种属 | human |
Uniprot ID |
分子量 | Actual: 49 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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