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Anti-VCAN Antibody (9D241) 是一种 Rabbit 抗体,靶向 VCAN。Anti-VCAN Antibody (9D241) 可用于 IHC,WB。
Anti-VCAN Antibody (9D241) 是一种 Rabbit 抗体,靶向 VCAN。Anti-VCAN Antibody (9D241) 可用于 IHC,WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,495 | 5日内发货 |
产品描述 | Anti-VCAN Antibody (9D241) is a Rabbit antibody targeting VCAN. Anti-VCAN Antibody (9D241) can be used in IHC,WB. |
别名 | Versican core protein, VCAN, PG-M, Large fibroblast proteoglycan, Glial hyaluronate-binding protein (GHAP), CSPG2, Chondroitin sulfate proteoglycan core protein 2 (Chondroitin sulfate proteoglycan 2) |
Ig Type | IgG |
交叉反应 | Human,Mouse |
验证活性 | 1. Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-Versican antibody. Counter stained with hematoxylin. 2. Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-Versican antibody. Counter stained with hematoxylin. |
应用 | |
推荐剂量 | IHC: 1:50-200 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Versican (chondroitin sulfate proteoglycan 2) is a large extracellular matrix proteoglycan involved in cell growth and differentiation. Important as a structural molecule, versican creates loose and hydrated matrices during key events in development and disease. The protein contains hyaluronic acid and glycosminoglycan-binding domains, epidermal growth factor-like repeats, a lectin-like sequence and a complement regulatory protein-like domain. Splice variants differ greatly in length and degree of modification by glycosaminoglycan chains. Accumulation around smooth muscle cells in lesions of atherosclerosis, suggests a role for versican in atherogenesis. Versican, differentially expressed in human melanoma, plays a role in tumor development and may be a reliable marker for clinical diagnosis. The organization of HA- and versican-rich pericellular matrices may faciliatate migration and mitosis by diminishing cell surface adhesivity and affecting cell shape through steric exclusion and the viscous properties of HA proteoglycan gels. The human verisican gene maps to chromosome 5q14.3. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 373/265/182/74 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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