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Anti-Her2/ERBB2 Antibody-PE (7Q527)
还可以产品编号 TMAY-03426P
Anti-Her2/ERBB2 Antibody-PE (7Q527) 是一种 PE-conjugated Rabbit 抗体，靶向 Her2/ERBB2。Anti-Her2/ERBB2 Antibody-PE (7Q527) 可用于 FCM。
Anti-Her2/ERBB2 Antibody-PE (7Q527)
Anti-Her2/ERBB2 Antibody-PE (7Q527)
还可以产品编号 TMAY-03426P
Anti-Her2/ERBB2 Antibody-PE (7Q527) 是一种 PE-conjugated Rabbit 抗体，靶向 Her2/ERBB2。Anti-Her2/ERBB2 Antibody-PE (7Q527) 可用于 FCM。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Her2/ERBB2 Antibody-PE (7Q527) is a PE-conjugated Rabbit antibody targeting Her2/ERBB2. Anti-Her2/ERBB2 Antibody-PE (7Q527) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 7Q527 |
| 交叉反应 | Mouse |
| 验证活性 | Flow cytometric analysis of Mouse Her2/ERBB2 expression on 3T3-L1 cells. Cells were stained with PE-conjugated anti-Mouse Her2/ERBB2. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | FCM |
| 推荐剂量 | 10 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse HER2 / ErbB2 / CD340 (rM HER2 / ErbB2 / CD340; TMPY-02314; P70424; Met1-Thr653) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| 研究背景 | Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth factors due to the lacking of ligand binding domain of its own and autoinhibited constitutively. However, HER2 forms a heterodimer with other ligand-bound EGF receptor family members, therefore stabilizes ligand binding and enhances kinase-mediated activation of downstream molecules. HER2 plays a key role in development, cell proliferation and differentiation. HER2 gene has been reported to associate with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate, ovarian, lung cancers and so on.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| 偶联 | PE |
| 其他可选修饰符 | Unconjugated |
| 可提供抗体种类 | 2 |
| 免疫原 | Recombinant Mouse HER2 / ErbB2 / CD340 Protein (TMPY-02314) |
| 抗原种属 | Mouse |
| 研究领域 | Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs) |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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