Powder: -20°C for 3 years | In solvent: -80°C for 1 year
L-Phenylalanine-15N ((S)-2-Amino-3-phenylpropionic acid-15N) 是 15N 标记的 L-Phenylalanine。L-Phenylalanine 是从大肠杆菌中分离出来的一种必需氨基酸。 L-Phenylalanine 广泛用于食品香精和药物的生产。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 109 | 现货 | ||
5 mg | ¥ 222 | 现货 | ||
10 mg | ¥ 347 | 现货 | ||
25 mg | ¥ 563 | 现货 | ||
50 mg | ¥ 827 | 现货 |
产品描述 | L-Phenylalanine-15N ((S)-2-Amino-3-phenylpropionic acid-15N) is the 15N-labeled L-Phenylalanine. L-Phenylalanine is an essential amino acid isolated from Escherichia coli . L-Phenylalanine is a α2δ subunit of voltage-dependent Ca + channels antagonist with a K i of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) ( K B of 573 μM ) and non-NMDARs , respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals. |
体外活性 | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Studies involving the human use of drugs labeled with deuterium suggest that these compounds may offer some advantages when compared with their nondeuterated counterparts. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. |
别名 | L-苯丙氨酸 15N, (S)-2-Amino-3-phenylpropionic acid-15N, L-Phenylalanine-15N |
分子量 | 166.18 |
分子式 | C9H11NO2 |
CAS No. | 29700-34-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: < 1.66 mg/mL (10 mM, insoluble or slightly soluble)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 6.0176 mL | 30.0879 mL | 60.1757 mL | 150.4393 mL |
5 mM | 1.2035 mL | 6.0176 mL | 12.0351 mL | 30.0879 mL | |
10 mM | 0.6018 mL | 3.0088 mL | 6.0176 mL | 15.0439 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
L-Phenylalanine-15N 29700-34-3 Membrane transporter/Ion channel Metabolism Calcium Channel Ca2+ channels L Phenylalanine 15N L-苯丙氨酸 15N Inhibitor (S)-2-Amino-3-phenylpropionic acid-15N iGluR inhibit Ca channels Endogenous Metabolite Ionotropic glutamate receptors LPhenylalanine15N 2-Amino-3-phenylpropionic acid-15N inhibitor