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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-MAD1 Antibody (5Y280)

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货号 TMAB-08496

Anti-MAD1 Antibody (5Y280) 是一种 Rabbit 抗体，靶向 MAD1。Anti-MAD1 Antibody (5Y280) 可用于 WB。

Anti-MAD1 Antibody (5Y280)

Anti-MAD1 Antibody (5Y280)

一键复制产品信息
Rating icon 还可以
货号 TMAB-08496

Anti-MAD1 Antibody (5Y280) 是一种 Rabbit 抗体，靶向 MAD1。Anti-MAD1 Antibody (5Y280) 可用于 WB。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-MAD1 Antibody (5Y280) is a Rabbit antibody targeting MAD1. Anti-MAD1 Antibody (5Y280) can be used in WB.
Ig Type
IgG
克隆号
5Y280
反应种属
Human,Mouse,Rat
应用WB
推荐剂量
WB: 1:1000-2000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, centrosome. Cytoplasm, cytoskeleton, spindle. Note=From the beginning to the end of mitosis, it is seen to move from a diffusely nuclear distribution to the centrosome, to the spindle midzone and finally to the midbody. Co-localizes with NEK2 at the kinetochore.
组织特异性Expressed weakly at G0/G1 and highly at late S and G2/M phase.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate.Forms a heterotetrameric complex with the closed conformation form of MAD2L1 (C-MAD2) at unattached kinetochores during prometaphase, recruits an open conformation of MAD2L1.
抗原信息
免疫原
A synthesized peptide: human MAD1
抗原种属
Human
基因名称
MAD1L1
基因ID
8379
蛋白名称
Mitotic spindle assembly checkpoint protein MAD1
Uniprot ID
Q9Y6D9
功能
Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. May recruit MAD2L1 to unattached kinetochores. Has a role in the correct positioning of the septum. Required for anchoring MAD2L1 to the nuclear periphery. Binds to the TERT promoter and represses telomerase expression, possibly by interfering with MYC binding.
化学信息
分子量Theoretical: 83 kDa. Actual: 80 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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