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Anti-FMN1 Polyclonal Antibody 2

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货号 TMAB-06084

Anti-FMN1 Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 FMN1。Anti-FMN1 Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。

Anti-FMN1 Polyclonal Antibody 2

Anti-FMN1 Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
货号 TMAB-06084

Anti-FMN1 Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 FMN1。Anti-FMN1 Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-FMN1 Polyclonal Antibody 2 is a Rabbit antibody targeting FMN1. Anti-FMN1 Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse,Dog,Cow,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasm. Cell junction, adherens junction; Peripheral membrane protein; Cytoplasmic side.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The temporal genetic hierarchy influencing normal limb development can deregulate and mediate mammalian developmental syndromes. In mice, the limb deformity (ld) locus influences normal limb development and gives rise to alternative mRNAs that can translate into a family of proteins known as formins. Formins play a crucial role in cytoskeletal reorganization by influencing Actin filament assembly. Formins co-localize with the actin cytoskeleton and can translocate into the cell cytosol and into the nucleus in an HGF-dependent manner. Vertebrate nuclear formins can control polarizing activity in limb buds through establishment of a Sonic hedgehog/FGF-4 feedback loop. Deficiency mutations at the mammalian ld locus lead to profound developmental defects in limb and kidney formation. The human Formin 1 and 2 genes map to chromosome 15q13.3 and 1q43, respectively.
抗原信息
免疫原
KLH conjugated synthetic peptide: human FMN1/Formin 1
抗原种属
Human
基因名称
FMN1
基因ID
蛋白名称
Formin-1
Uniprot ID
功能
FMN1 plays a role in the formation of adherens junction and the polymerization of linear actin cables. Interacts with alpha-catenin and may interact with tubulin.
化学信息
分子量Theoretical: 157 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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