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Anti-DFFA Monoclonal Antibody (8J396) 是一种 Mouse 抗体,靶向 DFFA。Anti-DFFA Monoclonal Antibody (8J396) 可用于 FCM。
别名 ICAD, DFF-45, DFF1
Anti-DFFA Monoclonal Antibody (8J396) 是一种 Mouse 抗体,靶向 DFFA。Anti-DFFA Monoclonal Antibody (8J396) 可用于 FCM。

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| 产品描述 | Anti-DFFA Monoclonal Antibody (8J396) is a Mouse antibody targeting DFFA. Anti-DFFA Monoclonal Antibody (8J396) can be used in FCM. |
| 别名 | ICAD, DFF-45, DFF1 |
| Ig Type | IgG1 |
| 克隆号 | 8J396 |
| 反应种属 | Human |
| 应用 | FCM |
| 推荐剂量 | FCM: 1/200-1/400 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide |
| 浓度 | 1 mg/ml |
| 研究背景 | Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of human DFFA (AA: 179-331) expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | DFFA |
| 基因ID | |
| 蛋白名称 | DNA fragmentation factor subunit alpha |
| Uniprot ID |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |