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Anti-Proteoglycan 4 Polyclonal Antibody

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Anti-Proteoglycan 4 Polyclonal Antibody
产品编号 TMAB-01582

Anti-Proteoglycan 4 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Proteoglycan 4。Anti-Proteoglycan 4 Polyclonal Antibody 可用于 WB。

Anti-Proteoglycan 4 Polyclonal Antibody

Anti-Proteoglycan 4 Polyclonal Antibody

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Anti-Proteoglycan 4 Polyclonal Antibody
产品编号 TMAB-01582

Anti-Proteoglycan 4 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Proteoglycan 4。Anti-Proteoglycan 4 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
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产品介绍

生物活性
产品描述
Anti-Proteoglycan 4 Polyclonal Antibody is a Rabbit antibody targeting Proteoglycan 4. Anti-Proteoglycan 4 Polyclonal Antibody can be used in WB.
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
Sample:
Lane 1: Mouse Liver tissue lysates
Lane 2: Human LO2 cell lysates
Primary: Anti-Lubricin (TMAB-01582) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 152 kDa
Observed band size: 160 kDa
应用
WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景Lubricin, also designated proteoglycan-4 or megakaryocyte stimulating factor, is important for boundary lubrication within articulating joints. It is a disulfide-linked homodimer (between Cysteine 1146 and Cysteine 1403) that is essential for protein cleavage. Lubricin inhibits synovial cell adhesion to the cartilage surface, but also prevents the deposition of proteins from synovial fluid onto cartilage. Lubricin is highly expressed in cartilage, liver and synovial tissue. Defects in the gene encoding for lubricin can cause Jakobs syndrome, also designated camptodactyly-arthropathy-coxa vara-pericarditis syndrome (CACP). CACP is an autosomal recessive disorder characterized by joint failure associated with noninflammatory synoviocyte hyperplasia and subinitimal fibrosis of the synovial capsule. Lubricin undergoes different levels of glycosylation and may be detected at varying molecular weights.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Lubricin/SZP
抗原种属
Human
基因ID
10216
Uniprot ID
Q92954
研究领域
Bone
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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