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Anti-Phospho-CDC27 (Thr244) Polyclonal Antibody

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货号 TMAB-10460

Anti-Phospho-CDC27 (Thr244) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-CDC27 (Thr244)。Anti-Phospho-CDC27 (Thr244) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Phospho-CDC27 (Thr244) Polyclonal Antibody

Anti-Phospho-CDC27 (Thr244) Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-10460

Anti-Phospho-CDC27 (Thr244) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-CDC27 (Thr244)。Anti-Phospho-CDC27 (Thr244) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-CDC27 (Thr244) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CDC27 (Thr244). Anti-Phospho-CDC27 (Thr244) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Dog,Pig,Horse,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and thus may be involved in controlling the timing of mitosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
KLH conjugated Synthesised phosphopeptide: human CDC27 around the phosphorylation site of Thr244
抗原种属
Human
基因名称
CDC27
基因ID
996
蛋白名称
Cell division cycle protein 27 homolog
Uniprot ID
P30260
功能
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
化学信息
分子量Theoretical: 92 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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