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Anti-E-Cadherin/Cadherin-1 Polyclonal Antibody 3
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产品编号 TMAB-00586
Anti-E-Cadherin/Cadherin-1 Polyclonal Antibody 3 是一种 Rabbit 抗体，靶向 E-Cadherin/Cadherin-1。Anti-E-Cadherin/Cadherin-1 Polyclonal Antibody 3 可用于 WB,FCM。
Anti-E-Cadherin/Cadherin-1 Polyclonal Antibody 3
Anti-E-Cadherin/Cadherin-1 Polyclonal Antibody 3
还可以产品编号 TMAB-00586
Anti-E-Cadherin/Cadherin-1 Polyclonal Antibody 3 是一种 Rabbit 抗体，靶向 E-Cadherin/Cadherin-1。Anti-E-Cadherin/Cadherin-1 Polyclonal Antibody 3 可用于 WB,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
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产品介绍
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抗原信息
| 产品描述 | Anti-E-Cadherin/Cadherin-1 Polyclonal Antibody 3 is a Rabbit antibody targeting E-Cadherin/Cadherin-1. Anti-E-Cadherin/Cadherin-1 Polyclonal Antibody 3 can be used in WB,FCM. |
| Ig Type | IgG |
| 交叉反应 | Human (predicted:Horse,Cow,Pig,Dog,Chicken,Rat,Mouse) |
| 验证活性 | 1. Histogram of MCF7 cells stained with anti-E-cadherin (orange), isotype control antibody (green), secondary antibody only (blue) and unstained (red). 2. Sample: Lane 1: MDA-MB-231 (Human) Cell Lysate at 30 μg Lane 2: A431 (Human) Cell Lysate at 30 μg Lane 3: A549 (Human) Cell Lysate at 30 μg Lane 4: HepG2 (Human) Cell Lysate at 30 μg Primary: Anti-E cadherin (TMAB-00586) at 1/500 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 125 kDa Observed band size: 120 kDa |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000; FCM: 1μg/Test |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cell junction. Cell membrane; Single-pass type I membrane protein. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究背景 | This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16. [provided by RefSeq, Nov 2015] |
| 免疫原 | KLH conjugated synthetic peptide: human E-cadherin |
| 抗原种属 | Human |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | Cadherins,Kidney development,e cadherin,Cadherins,Calcium Binding Proteins |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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