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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-DICER1 Polyclonal Antibody

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货号 TMAB-05145

Anti-DICER1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DICER1。Anti-DICER1 Polyclonal Antibody 可用于 ICC/IF。

Anti-DICER1 Polyclonal Antibody

Anti-DICER1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-05145

Anti-DICER1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DICER1。Anti-DICER1 Polyclonal Antibody 可用于 ICC/IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-DICER1 Polyclonal Antibody is a Rabbit antibody targeting DICER1. Anti-DICER1 Polyclonal Antibody can be used in ICC/IF.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Pig,Cow,Horse)
应用ICC/IF
推荐剂量
ICC/IF: 1:50-200
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010]
抗原信息
免疫原
KLH conjugated synthetic peptide: human DICER1/Dicer
抗原种属
Human
基因名称
DICER1
基因ID
23405
蛋白名称
Endoribonuclease Dicer
Uniprot ID
Q9UPY3
功能
Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, EIF2C2/AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto EIF2C2/AGO2. EIF2C2/AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. Also cleaves double-stranded RNA to produce short interfering RNAs (siRNAs) which target the selective destruction of complementary RNAs.
化学信息
分子量Theoretical: 217 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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