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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Huntingtin Antibody (3A980)

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货号 TMAB-07454

Anti-Huntingtin Antibody (3A980) 是一种 Rabbit 抗体，靶向 Huntingtin。Anti-Huntingtin Antibody (3A980) 可用于 WB,IHC-P,IHC-Fr,IF,FCM。

Anti-Huntingtin Antibody (3A980)

Anti-Huntingtin Antibody (3A980)

一键复制产品信息
Rating icon 还可以
货号 TMAB-07454

Anti-Huntingtin Antibody (3A980) 是一种 Rabbit 抗体，靶向 Huntingtin。Anti-Huntingtin Antibody (3A980) 可用于 WB,IHC-P,IHC-Fr,IF,FCM。

规格价格库存数量
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-Huntingtin Antibody (3A980) is a Rabbit antibody targeting Huntingtin. Anti-Huntingtin Antibody (3A980) can be used in WB,IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
克隆号
3A980
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrIFFCM
推荐剂量
WB: 1:1000-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1μg/Test
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus. The mutant Huntingtin protein colocalizes with AKAP8L in the nuclear matrix of Huntington's disease neurons.
组织特异性Expressed in the brain cortex (at protein level). Widely expressed with the highest level of expression in the brain (nerve fibers, varicosities, and nerve endings). In the brain, the regions where it can be mainly found are the cerebellar cortex, the neocortex, the striatum, and the hippocampal formation.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Huntingtin is a protein that contains a polyglutamine region. When the number of glutamine repeats exceeds 35, the gene encodes a version of Huntingtin that leads to Huntington’s disease (HD). When the polyglutamine stretch is mutated, Huntingtin acts within the nucleus to induce neurodegeneration by a cell-specific apoptotic mechanism. Loss of Huntingtin activity is unlikely to be the cause of HD, and it has been proposed that the expanded glutamine repeat region may induce an abnormal interaction between the mutant protein and other cellular proteins. Huntingtin interacts with a variety of proteins including HAP1, glyceraldehyde phosphate dehydrogenase (GAPDH) and HIP1.
抗原信息
免疫原
A synthesized peptide: human Huntingtin
抗原种属
Human
基因名称
HTT
基因ID
3064
蛋白名称
Huntingtin
Uniprot ID
P42858
功能
May play a role in microtubule-mediated transport or vesicle function.
化学信息
分子量Theoretical: 347 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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