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Anti-CAMK1 Antibody (4H22)
还可以产品编号 TMAY-02150
Anti-CAMK1 Antibody (4H22) 是一种 Rabbit 抗体，靶向 CAMK1。Anti-CAMK1 Antibody (4H22) 可用于 ELISA。
Anti-CAMK1 Antibody (4H22)
Anti-CAMK1 Antibody (4H22)
还可以产品编号 TMAY-02150
Anti-CAMK1 Antibody (4H22) 是一种 Rabbit 抗体，靶向 CAMK1。Anti-CAMK1 Antibody (4H22) 可用于 ELISA。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-CAMK1 Antibody (4H22) is a Rabbit antibody targeting CAMK1. Anti-CAMK1 Antibody (4H22) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 4H22 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human CAMKI / CAMK1 (rh CAMKI / CAMK1; TMPY-04415; NP_003647.1; Leu2-Leu370). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Calcium/calmodulin-dependent protein kinase or CaM kinases are serine/threonine-specific protein kinases that are primarily regulated by the Calcium/calmodulin complex. These kinases show a memory effect on activation. CaM kinases activity can outlast the intracellular calcium transient that is needed to activate it. Inneurons, this property is important for the induction of synaptic plasticity. Pharmacological inhibition of CaM kinases II blocks the induction of long-term potentiation. Upon activation, CaM kinases II phosphorylates postsynaptic glutamate receptors and changes the electrical properties of the synapse. Calcium/calmodulin-dependent protein kinase type 1D, also known as CaM kinase I delta, CaM kinase ID, CaMKI-like protein kinase, CKLiK and CAMK1D, is a member of theprotein kinase superfamily and CaMK subfamily. It contains oneprotein kinase domain. CAMK1D is broadly expressed. It is highly and mostly expressed in polymorphonuclear leukocytes (neutrophilic and eosinophilic granulocytes) while little or no expression is observed in monocytes and lymphocytes. Engineered overexpression of CAMK1D in non-tumorigenic breast epithelial cells led to increased cell proliferation, and molecular and phenotypic alterations indicative of epithelial-mesenchymal transition (EMT), including loss of cell-cell adhesions and increased cell migration and invasion. CAMK1D is a potential therapeutic target with particular relevance to clinically unfavorable basal-like tumors. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human CAMKI / CAMK1 protein (TMPY-04415) |
| 抗原种属 | Human |
| 研究领域 | Calcium-binding Proteins and Related Molecules |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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