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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-COQ10B Polyclonal Antibody

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货号 TMAB-04581

Anti-COQ10B Polyclonal Antibody 是一种 Rabbit 抗体，靶向 COQ10B。Anti-COQ10B Polyclonal Antibody 可用于 WB。

Anti-COQ10B Polyclonal Antibody

Anti-COQ10B Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-04581

Anti-COQ10B Polyclonal Antibody 是一种 Rabbit 抗体，靶向 COQ10B。Anti-COQ10B Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-COQ10B Polyclonal Antibody is a Rabbit antibody targeting COQ10B. Anti-COQ10B Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep, Orangutan)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Mitochondrion inner membrane; Peripheral membrane protein; Matrix side
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景COQ10B, Coenzyme Q10, is a 247 amino acid protein encoded by the human gene COQ10B. COQ10B is a mitochondrial protein that belongs to the COQ10 family. COQ10B is an essential biological cofactor which increases brain mitochondrial concentration and exerts neuroprotective effects. Plasma COQ10B levels decrease in patients with advanced chronic heart failure (CHF) while COQ10B levels in hyperthyroid patients are found among the lowest detected in human diseases. Likewise, COQ10B is elevated in hypothyroid subjects, also in subclinical conditions, suggesting the usefulness of this index in assessing metabolic status in thyroid disorders. It is believed that secretion of adrenal hormones is in some way related to COQ10B levels, both in augmented and reduced conditions. However, since thyroid hormones have an important role in modulating COQ10B levels and metabolism, when coexistent, thyroid deficiency seems to play a prevalent role in comparison with adrenal deficiency.
抗原信息
免疫原
KLH conjugated synthetic peptide: human COQ10B
抗原种属
Human
基因名称
COQ10B
基因ID
80219
蛋白名称
Coenzyme Q-binding protein COQ10 homolog B, mitochondrial
Uniprot ID
Q9H8M1
功能
COQ10 (Coenzyme Q10) is found in a wide variety of foods and is synthesized in all tissues. The de novo biosynthesis of COQ10, from its precursor tyrosine, is a multistage process that requires at least eight vitamins and several trace elements. More complex enzymes have an absolute dependancy on 'cofactors', a large group of molecules to which the coenzymes belong, for their catalyitic function. Coenzyme Q10 is the cofactor for, but not limited to, several mitochondrial enzymes that are central to the supply of adenosine triphosphate (ATP). In addition, COQ10 in its reduced form is a potent antioxidant, and in this capacity, a reduction in COQ10 levels are associtated with a variety of degenerative process including skin aging and neurodegenerative conditions such as Alzhiemer's, Huntingdon's and Parkinson's diseases.
化学信息
分子量Theoretical: 23 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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