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Anti-Phospho-eIF4E (Ser209) Polyclonal Antibody 2

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货号 TMAB-10633

Anti-Phospho-eIF4E (Ser209) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-eIF4E (Ser209)。Anti-Phospho-eIF4E (Ser209) Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,IF,FCM。

Anti-Phospho-eIF4E (Ser209) Polyclonal Antibody 2

Anti-Phospho-eIF4E (Ser209) Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
货号 TMAB-10633

Anti-Phospho-eIF4E (Ser209) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-eIF4E (Ser209)。Anti-Phospho-eIF4E (Ser209) Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,IF,FCM。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-eIF4E (Ser209) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-eIF4E (Ser209). Anti-Phospho-eIF4E (Ser209) Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Chicken,Dog,Pig,Cow,Horse,Rabbit,Zebrafish)
应用WBIHC-PIHC-FrIFFCM
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 0.2μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm, P-body.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景eIF4E, a protein modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. eIF4E also influences the overall rate of translation. eIF4E binds to the 7 methyl GTP cap structure of eukaryotic mRNAs. Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and/or RNA. Phosphorylation also enhances the interaction of eIF4E with eIF4G, which form a complex known as eIF4F. eIF4E phosphorylation is correlated with increased translational rate in a number of cell types. Several kinases are currently being investigated as potential regulators of eIF4E including PKC and/or the MAP kinase activated Mnk.
抗原信息
免疫原
KLH conjugated Synthesised phosphopeptide: human eIF4E around the phosphorylation site of Ser209
抗原种属
Human
基因名称
EIF4E
基因ID
1977
蛋白名称
Eukaryotic translation initiation factor 4E
Uniprot ID
P06730
功能
Its translation stimulation activity is repressed by binding to the complex CYFIP1-FMR1 (By similarity). Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap.
化学信息
分子量Theoretical: 24 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器
  • 配液 计算器
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