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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-BNP Polyclonal Antibody

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货号 TMAB-03182

Anti-BNP Polyclonal Antibody 是一种 Rabbit 抗体，靶向 BNP。Anti-BNP Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-BNP Polyclonal Antibody

Anti-BNP Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-03182

Anti-BNP Polyclonal Antibody 是一种 Rabbit 抗体，靶向 BNP。Anti-BNP Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-BNP Polyclonal Antibody is a Rabbit antibody targeting BNP. Anti-BNP Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted.
组织特异性Brain and also in atria, but at much lower levels than ANP.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Brain natriuretic peptide (BNP), also known as B-type natriuretic peptide, is a hormone secreted by cardiomyocytes in the heart ventricles in response to stretching caused by increased ventricular blood volume. The 32-amino acid polypeptide BNP is secreted attached to a 76–amino acid N-terminal fragment in the prohormone called NT-proBNP (BNPT), which is biologically inactive. Once released, BNP binds to and activates the atrial natriuretic factor receptor NPRA, and to a lesser extent NPRB, in a fashion similar to atrial natriuretic peptide (ANP) but with 10-fold lower affinity. The biological half-life of BNP, however, is twice as long as that of ANP, and that of NT-proBNP is even longer, making these peptides better targets than ANP for diagnostic blood testing.
抗原信息
免疫原
KLH conjugated synthetic peptide: human BNP 32
抗原种属
Human
基因名称
NPPB
基因ID
4879
蛋白名称
Natriuretic peptides B
Uniprot ID
P16860
功能
Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
化学信息
分子量Theoretical: 3.5 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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