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Anti-Serpin B6 Antibody (6G141)

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产品编号 TMAY-02421

Anti-Serpin B6 Antibody (6G141) 是一种 Rabbit 抗体,靶向 Serpin B6。Anti-Serpin B6 Antibody (6G141) 可用于 ELISA。

Anti-Serpin B6 Antibody (6G141)

Anti-Serpin B6 Antibody (6G141)

Rating icon 还可以
产品编号 TMAY-02421

Anti-Serpin B6 Antibody (6G141) 是一种 Rabbit 抗体,靶向 Serpin B6。Anti-Serpin B6 Antibody (6G141) 可用于 ELISA。

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产品介绍

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产品描述
Anti-Serpin B6 Antibody (6G141) is a Rabbit antibody targeting Serpin B6. Anti-Serpin B6 Antibody (6G141) can be used in ELISA.
Ig Type
Monoclonal Rabbit IgG
克隆号
6G141
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human SerpinB6 (rh SerpinB6; TMPY-02242; AAB30320.1; Asp 2-Pro 376).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景SerpinB6, also known as Cytoplasmic antiproteinase, Peptidase inhibitor 6, Placental thrombin inhibitor, SERPINB6 and PI-6, is a cytoplasm protein that belongs to the serpin family and Ov-serpin subfamily. SerpinB6 / PI-6 is an inhibitor of cathepsin G, kallikrein-8 and thrombin. It may play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss. SerpinB6 / PI-6 is expressed in keratinocytes (at protein level). It is also found in placenta, cardiac muscle, lung, liver, kidney and pancreas. SerpinB6 / PI-6 is expressed in the inner ear hair cells. It’s expressed abundantly by normal mast cells in different tissues and by mast cells in mastocytoma lesions. SerpinB6 / PI-6 may be involved in the regulation of serine proteinases present in the brain or extravasated from the blood. Defects in SerpinB6 are the cause of deafness autosomal recessive type 91 which is a form of non-syndromic deafness characterized by progressive and age-dependent sensorineural hearing loss. Vestibular function is normal.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human SerpinB6 protein (TMPY-02242)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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