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Anti-Beta tubulin cofactor D Polyclonal Antibody

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货号 TMAB-03120

Anti-Beta tubulin cofactor D Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Beta tubulin cofactor D。Anti-Beta tubulin cofactor D Polyclonal Antibody 可用于 WB。

Anti-Beta tubulin cofactor D Polyclonal Antibody

Anti-Beta tubulin cofactor D Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-03120

Anti-Beta tubulin cofactor D Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Beta tubulin cofactor D。Anti-Beta tubulin cofactor D Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-Beta tubulin cofactor D Polyclonal Antibody is a Rabbit antibody targeting Beta tubulin cofactor D. Anti-Beta tubulin cofactor D Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Chicken,Rabbit)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell junction, tight junction (Bysimilarity). Lateral cell membrane (By similarity). Cytoplasm (Bysimilarity). Cell junction, adherens junction (By similarity).Note=Localized in cell-cell contacts (By similarity).
组织特异性Ubiquitously expressed.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Tubulin-folding protein; involved in the first step of the tubulin folding pathway. Modulates microtubule dynamics by capturing GTP-bound beta-tubulin (TUBB). Acts as a GTPase-activating protein (GAP) for ARL2. Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes epithelial cell detachment, a process antagonized by ARL2. Induces tight adherens and tight junctions disassembly at the lateral cell membrane.
抗原信息
免疫原
KLH conjugated synthetic peptide: human TBCD/Beta tubulin cofactor D
抗原种属
Human
基因名称
TBCD
基因ID
蛋白名称
Tubulin-specific chaperone D
Uniprot ID
功能
Tubulin-folding protein; involved in the first step ofthe tubulin folding pathway. Modulates microtubule dynamics bycapturing GTP-bound beta-tubulin (TUBB). Acts as aGTPase-activating protein (GAP) for ARL2. Its ability to interactwith beta tubulin is regulated via its interaction with ARL2.Induces microtubule disruption in absence of ARL2. Increasesdegradation of beta tubulin, when overexpressed in polarized cells.Promotes epithelial cell detachment, a process antagonized by ARL2.Induces tight adherens and tight junctions disassembly at thelateral cell membrane.
化学信息
分子量Theoretical: 133 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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