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Anti-RNF20 Antibody (4H387)

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货号 TMAB-12310

Anti-RNF20 Antibody (4H387) 是一种 Rabbit 抗体,靶向 RNF20。Anti-RNF20 Antibody (4H387) 可用于 WB,ICC/IF,IP,FCM。

Anti-RNF20 Antibody (4H387)

Anti-RNF20 Antibody (4H387)

一键复制产品信息
Rating icon 还可以
货号 TMAB-12310

Anti-RNF20 Antibody (4H387) 是一种 Rabbit 抗体,靶向 RNF20。Anti-RNF20 Antibody (4H387) 可用于 WB,ICC/IF,IP,FCM。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍


生物活性
产品描述
Anti-RNF20 Antibody (4H387) is a Rabbit antibody targeting RNF20. Anti-RNF20 Antibody (4H387) can be used in WB,ICC/IF,IP,FCM.
Ig Type
IgG
克隆号
4H387
反应种属
Human (predicted:Mouse)
应用WBICC/IFIPFCM
推荐剂量
WB: 1:1000-2000; ICC/IF: 1:50-200; IP: 1:20-50; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nuclear
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role inb histone code and gene regulation.
抗原信息
免疫原
A synthesized peptide: human RNF20
抗原种属
Human
基因名称
RNF20
基因ID
蛋白名称
E3 ubiquitin-protein ligase BRE1A
Uniprot ID
功能
Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role in histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B; reports about the cooperation with UBE2E1/UBCH are contradictory. Required for transcriptional activation of Hox genes. Recruited to the MDM2 promoter, probably by being recruited by p53/TP53, and thereby acts as a transcriptional coactivator.
化学信息
分子量Theoretical: 114 kDa. Actual: 114 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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