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Anti-ENTPD5 Antibody-HRP (3U803)

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产品编号 TMAY-01724H

Anti-ENTPD5 Antibody-HRP (3U803) 是一种 HRP-conjugated Rabbit 抗体,靶向 ENTPD5。Anti-ENTPD5 Antibody-HRP (3U803) 可用于 ELISA。

Anti-ENTPD5 Antibody-HRP (3U803)

Anti-ENTPD5 Antibody-HRP (3U803)

Rating icon 还可以
产品编号 TMAY-01724H

Anti-ENTPD5 Antibody-HRP (3U803) 是一种 HRP-conjugated Rabbit 抗体,靶向 ENTPD5。Anti-ENTPD5 Antibody-HRP (3U803) 可用于 ELISA。

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产品介绍

生物活性
产品描述
Anti-ENTPD5 Antibody-HRP (3U803) is a HRP-conjugated Rabbit antibody targeting ENTPD5. Anti-ENTPD5 Antibody-HRP (3U803) can be used in ELISA.
Ig Type
Monoclonal Rabbit IgG
克隆号
3U803
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 0.1-1 μg/ml
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human ENTPD5 (rh ENTPD5; TMPY-02758; O75356; Met1-His428), and conjugated with horseradish-peroxidase (HRP).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Ectonucleoside triphosphate diphosphohydrolase 5 (ENTPD5), also known as CD39 antigen-like 4, ER-UDPase, Guanosine-diphosphatase ENTPD5, Nucleoside diphosphatase Uridine-diphosphatase ENTPD5. This hydrolase is expressed in response to phosphoinositide 3-kinase (PI3K) signaling. Activation of PI3K results in FOXO phosphorylation by AKT1 and loss of ENTPD5 transcriptional repression. It is Up-regulated in PTEN-deficient cells. Uridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation.ENTPD5 promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, ENTPD5 constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. ENTPD5 also hydrolyzes GDP and IDP but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. This enzyme Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling.
偶联与修饰
偶联
HRP
其他可选修饰符
Unconjugated
可提供抗体种类
2
抗原信息
免疫原
Recombinant Human ENTPD5 protein (TMPY-02758)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight.
运输方式Shipping with blue ice.

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