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Anti-PSGL-1/CD162 Antibody-PE (6E322)
还可以产品编号 TMAY-02647P
Anti-PSGL-1/CD162 Antibody-PE (6E322) 是一种 PE-conjugated Mouse 抗体，靶向 PSGL-1/CD162。Anti-PSGL-1/CD162 Antibody-PE (6E322) 可用于 FCM。
Anti-PSGL-1/CD162 Antibody-PE (6E322)
Anti-PSGL-1/CD162 Antibody-PE (6E322)
还可以产品编号 TMAY-02647P
Anti-PSGL-1/CD162 Antibody-PE (6E322) 是一种 PE-conjugated Mouse 抗体，靶向 PSGL-1/CD162。Anti-PSGL-1/CD162 Antibody-PE (6E322) 可用于 FCM。
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偶联与修饰
抗原信息
| 产品描述 | Anti-PSGL-1/CD162 Antibody-PE (6E322) is a PE-conjugated Mouse antibody targeting PSGL-1/CD162. Anti-PSGL-1/CD162 Antibody-PE (6E322) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 6E322 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human SELPLG(CD162) expression on human whole blood granulocytes. Cells were stained with purified anti-Human SELPLG(CD162), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable granulocytes. |
| 应用 | FCM |
| 推荐剂量 | 10 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human PSGL-1 / CD162 (rh PSGL-1 / CD162; TMPY-03531; Q14242-1; Met1-Gly295) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| 研究背景 | P-selectin glycoprotein ligand-1 (PSGL-1), also known as SELPLG or CD162, is the high affinity ounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. PSGL-1 is a mucin-type glycoprotein, expressed on leukocytes and platelets as a homodimer of two disulfide-linked subunits of ~12 kD. As cell adhesion molecules, multiple studies have shown that PSGL-1/ P-selectin interaction is required for the normal recruitment of leukocytes during inflammatory reactions, and also participates in hemostatic responses. PSGL-1 protein requires two distinct posttranslational modifications for the Ca2+-dependent recognition by the lectin domain of P-selectin, that is tyrosine sulfation and specific O-linked glycosylation (sialic acid and fucose). PSGL-1 can also bind to other two members of the selectin family, E-selectin (endothelial) and L-selectin (leukocyte), but binds best to P-selectin. |
| 偶联 | PE |
| 其他可选修饰符 | Unconjugated/APC |
| 可提供抗体种类 | 3 |
| 免疫原 | Recombinant Human PSGL-1 / CD162 Protein (TMPY-03531) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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