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Anti-FBP1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 FBP1。Anti-FBP1 Polyclonal Antibody 可用于 WB,ICC/IF,FCM。
Anti-FBP1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 FBP1。Anti-FBP1 Polyclonal Antibody 可用于 WB,ICC/IF,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,795 | 5日内发货 |
| 产品描述 | Anti-FBP1 Polyclonal Antibody is a Rabbit antibody targeting FBP1. Anti-FBP1 Polyclonal Antibody can be used in WB,ICC/IF,FCM. |
| Ig Type | IgG |
| 反应种属 | Human,Mouse (predicted:Rat,Dog,Pig,Horse,Rabbit) |
| 应用 | WBICC/IFFCM |
| 推荐剂量 | WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1μg/Test |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytosol;Extracellular region or secreted;Nucleus |
| 组织特异性 | Belongs to the FBPase class 1 family. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| 浓度 | 1mg/ml |
| 研究背景 | Fructose-1,6-bisphosphatase 1, a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis. [provided by RefSeq, Jul 2008] |
| 免疫原 | KLH conjugated synthetic peptide: human FBP1 |
| 抗原种属 | Human |
| 基因名称 | FBP1 |
| 基因ID | |
| 蛋白名称 | Fructose-1, 6-bisphosphatase 1 |
| Uniprot ID | |
| 功能 | Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain. |
| 分子量 | Theoretical: 37 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |