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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-USP22 Polyclonal Antibody

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货号 TMAB-14018

Anti-USP22 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 USP22。Anti-USP22 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-USP22 Polyclonal Antibody

Anti-USP22 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-14018

Anti-USP22 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 USP22。Anti-USP22 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
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100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-USP22 Polyclonal Antibody is a Rabbit antibody targeting USP22. Anti-USP22 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse,Chicken,Dog,Cow,Horse,Rabbit,Sheep,Xenopus laevis)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Moderately expressed in various tissues including heart and skeletal muscle, and weakly expressed in lung and liver.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. Through the use of a wide range of enzymes that can add or remove ubiquitin, the Ub pathway controls many intracellular processes such as signal transduction, transcriptional activation and cell cycle progression. USP22 (ubiquitin specific peptidase 22), also known as USP3L, is a 525 amino acid protein that contains one UBP-type zinc finger and functions to catalyze the conversion of a ubiquitin C-terminal thioester to free ubiquitin and thiol, a reaction that may influence several cellular processes. Via its catalytic activity, USP22 is thought to play an important role in cell cycle progression and may also serve as a cancer stem cell marker.
抗原信息
免疫原
KLH conjugated synthetic peptide: human USP22
抗原种属
Human
基因名称
USP22
基因ID
23326
蛋白名称
Ubiquitin carboxyl-terminal hydrolase 22
Uniprot ID
Q9UPT9
功能
Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.
化学信息
分子量Theoretical: 60 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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