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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-BANF1 Antibody (7K215)

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货号 TMAB-03023

Anti-BANF1 Antibody (7K215) 是一种 Rabbit 抗体，靶向 BANF1。Anti-BANF1 Antibody (7K215) 可用于 IHC-P,IHC-Fr,ICC/IF,IF,ELISA。

Anti-BANF1 Antibody (7K215)

Anti-BANF1 Antibody (7K215)

一键复制产品信息
Rating icon 还可以
货号 TMAB-03023

Anti-BANF1 Antibody (7K215) 是一种 Rabbit 抗体，靶向 BANF1。Anti-BANF1 Antibody (7K215) 可用于 IHC-P,IHC-Fr,ICC/IF,IF,ELISA。

规格价格库存数量
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,495
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
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产品介绍

生物活性
产品描述
Anti-BANF1 Antibody (7K215) is a Rabbit antibody targeting BANF1. Anti-BANF1 Antibody (7K215) can be used in IHC-P,IHC-Fr,ICC/IF,IF,ELISA.
Ig Type
IgG
克隆号
7K215
反应种属
Human,Mouse,Rat
应用IHC-PIHC-FrICC/IFIFELISA
推荐剂量
IHC-P: 1:50-200; IHC-Fr: 1:50-200; ICC/IF: 1:50-200; IF: 1:50-200; ELISA: 1:5000-10000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasm. Chromosome. Significantly enriched at the nuclear inner membrane, diffusely throughout the nucleus during interphase and concentrated at the chromosomes during the M-phase. May be included in HIV-1 virions via its interaction with viral GAG polyprotein. Tissue Specificity : Widely expressed. Expressed in colon, brain, heart, kidney, liver, lung, ovary, pancreas, placenta, prostate, skeletal muscle, small intestine, spleen and testis. Not detected in thymus and peripheral blood leukocytes.
组织特异性Widely expressed. Expressed in colon, brain, heart, kidney, liver, lung, ovary, pancreas, placenta, prostate, skeletal muscle, small intestine, spleen and testis. Not detected in thymus and peripheral blood leukocytes.
构建方式Recombinant Antibody
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Barrier-to-autointegration factor (BAF) binds non-specifically to double stranded DNA, possibly to play a role in tissue- or cell type-specific gene expression by interacting with different homeodomain transcription factors. BAF compresses chromatin structure and interacts with the LEM domain of nuclear proteins to play a crucial role in membrane recruitment and chromatin decondensation during nuclear assembly. Additionally, retroviruses like HIV-1 incorporate BAF from host cells into preintegration complexes (PICs) to prevent autointegration of retroviral DNA and thereby promote integration of retroviral DNA into the host chromosome.
抗原信息
免疫原
Recombinant Protein: human BANF1
抗原种属
Human
基因名称
BANF1
基因ID
8815
蛋白名称
Barrier-to-autointegration factor
Uniprot ID
O75531
功能
Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non-specific dsDNA-binding sites which may promote DNA cross-bridging. Exploited by retroviruses for inhibiting self-destructing autointegration of retroviral DNA, thereby promoting integration of viral DNA into the host chromosome. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD.
化学信息
分子量Theoretical: 10 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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