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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-RanBP3 Antibody (4E390)

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货号 TMAB-12074

Anti-RanBP3 Antibody (4E390) 是一种 Rabbit 抗体，靶向 RanBP3。Anti-RanBP3 Antibody (4E390) 可用于 IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM。

Anti-RanBP3 Antibody (4E390)

Anti-RanBP3 Antibody (4E390)

一键复制产品信息
Rating icon 还可以
货号 TMAB-12074

Anti-RanBP3 Antibody (4E390) 是一种 Rabbit 抗体，靶向 RanBP3。Anti-RanBP3 Antibody (4E390) 可用于 IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-RanBP3 Antibody (4E390) is a Rabbit antibody targeting RanBP3. Anti-RanBP3 Antibody (4E390) can be used in IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM.
Ig Type
IgG
克隆号
4E390
反应种属
Human (predicted:Mouse)
应用IHC-PIHC-FrICC/IFIFIPFCM
推荐剂量
IHC-P: 1:100-200; IHC-Fr: 1:100-200; ICC/IF: 1:50-200; IF: 1:50-200; IP: 1:20-50; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus.
组织特异性Widely expressed with high levels in testis and heart.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner.
抗原信息
免疫原
A synthesized peptide: human RanBP3
抗原种属
Human
基因名称
RANBP3
基因ID
8498
蛋白名称
Ran-binding protein 3
Uniprot ID
Q9H6Z4
功能
Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. Negative regulator of TGF-beta signaling through interaction with the R-SMAD proteins, SMAD2 and SMAD3, and mediating their nuclear export.
化学信息
分子量Theoretical: 60 kDa. Actual: 70, 90 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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