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Anti-SCN10A/Nav1.8 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 SCN10A/Nav1.8。Anti-SCN10A/Nav1.8 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
Anti-SCN10A/Nav1.8 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 SCN10A/Nav1.8。Anti-SCN10A/Nav1.8 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,175 | 5日内发货 | |
100 μL | ¥ 1,960 | 5日内发货 | |
200 μL | ¥ 2,790 | 5日内发货 |
产品描述 | Anti-SCN10A/Nav1.8 Polyclonal Antibody is a Rabbit antibody targeting SCN10A/Nav1.8. Anti-SCN10A/Nav1.8 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
Ig Type | IgG |
交叉反应 | Rat (predicted:Human,Mouse,Dog,Pig,Cow) |
验证活性 | 1. Tissue/cell: rat spinal cord; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Incubation: Anti-SCN10A Polyclonal Antibody, Unconjugated (TMAB-01668) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining. 2. Tissue/cell: rat brain tissue;4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Incubation: Anti-SCN10A Polyclonal Antibody, Unconjugated (TMAB-01668) 1:200, overnight at 4°C; The secondary antibody was Goat Anti-Rabbit IgG, Cy3 conjugated used at 1:200 dilution for 40 minutes at 37°C. |
应用 | |
推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
亚细胞定位 | Membrane; Multi-pass membrane protein. Note=It can be translocated to the extracellular membrane through association with S100A10. |
构建方式 | Hybridoma Polyclonal Antibody |
纯化方式 | Protein A purified |
性状 | Liquid |
缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
研究背景 | Nav1.8 protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, Nav1.8 forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant sodium channel isoform. Nav1.8 plays a role in neuropathic pain mechanisms. |
免疫原 | KLH conjugated synthetic peptide: human SCN10A/NAV1.8 |
抗原种属 | Human |
基因ID | |
Uniprot ID | |
研究领域 | Sodium Channels,Nociception |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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