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Anti-SCN10A/Nav1.8 Polyclonal Antibody

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Anti-SCN10A/Nav1.8 Polyclonal Antibody
产品编号 TMAB-01668

Anti-SCN10A/Nav1.8 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 SCN10A/Nav1.8。Anti-SCN10A/Nav1.8 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-SCN10A/Nav1.8 Polyclonal Antibody

Anti-SCN10A/Nav1.8 Polyclonal Antibody

Rating icon 还可以
Anti-SCN10A/Nav1.8 Polyclonal Antibody
产品编号 TMAB-01668

Anti-SCN10A/Nav1.8 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 SCN10A/Nav1.8。Anti-SCN10A/Nav1.8 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-SCN10A/Nav1.8 Polyclonal Antibody is a Rabbit antibody targeting SCN10A/Nav1.8. Anti-SCN10A/Nav1.8 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
交叉反应
Rat (predicted:Human,Mouse,Dog,Pig,Cow)
验证活性
1. Tissue/cell: rat spinal cord; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min;
Incubation: Anti-SCN10A Polyclonal Antibody, Unconjugated (TMAB-01668) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining.
2. Tissue/cell: rat brain tissue;4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Blocking buffer (normal goat serum) at 37°C for 20 min;
Incubation: Anti-SCN10A Polyclonal Antibody, Unconjugated (TMAB-01668) 1:200, overnight at 4°C; The secondary antibody was Goat Anti-Rabbit IgG, Cy3 conjugated used at 1:200 dilution for 40 minutes at 37°C.
应用
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Multi-pass membrane protein. Note=It can be translocated to the extracellular membrane through association with S100A10.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景Nav1.8 protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, Nav1.8 forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant sodium channel isoform. Nav1.8 plays a role in neuropathic pain mechanisms.
抗原信息
免疫原
KLH conjugated synthetic peptide: human SCN10A/NAV1.8
抗原种属
Human
基因ID
Uniprot ID
研究领域
Sodium Channels,Nociception
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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