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Anti-CDC45 Antibody (6Q41)
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产品编号 TMAC-00772
别名 PORC-PI-1, PORC PI 1, Cell division cycle 45 like 2, Cell division cycle 45 like, cell division cycle 45 (S.cerevisiae homolog) like, Cell division control protein 45 homolog, CDC45L2, CDC45 related protein, CDC45 like, CDC45 cell division cycle 45 like, CDC45, CDC 45L, CDC 45
Anti-CDC45 Antibody (6Q41) 是一种 Rabbit 抗体，靶向 CDC45。Anti-CDC45 Antibody (6Q41) 可用于 WB,ICC/IF,IHC,FCM。
Anti-CDC45 Antibody (6Q41)
Anti-CDC45 Antibody (6Q41)
还可以产品编号 TMAC-00772 别名 PORC-PI-1, PORC PI 1, Cell division cycle 45 like 2, Cell division cycle 45 like, cell division cycle 45 (S.cerevisiae homolog) like, Cell division control protein 45 homolog, CDC45L2, CDC45 related protein, CDC45 like, CDC45 cell division cycle 45 like, CDC45, CDC 45L, CDC 45
Anti-CDC45 Antibody (6Q41) 是一种 Rabbit 抗体，靶向 CDC45。Anti-CDC45 Antibody (6Q41) 可用于 WB,ICC/IF,IHC,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,480 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-CDC45 Antibody (6Q41) is a Rabbit antibody targeting CDC45. Anti-CDC45 Antibody (6Q41) can be used in WB,ICC/IF,IHC,FCM. |
| 别名 | PORC-PI-1, PORC PI 1, Cell division cycle 45 like 2, Cell division cycle 45 like, cell division cycle 45 (S.cerevisiae homolog) like, Cell division control protein 45 homolog, CDC45L2, CDC45 related protein, CDC45 like, CDC45 cell division cycle 45 like, CDC45, CDC 45L, CDC 45 |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-CDC45 antibody. Counter stained with hematoxylin. 2. Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-CDC45 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-CDC45 antibody. Counter stained with hematoxylin. 4. ICC staining CDC45 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. ICC staining CDC45 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 6. ICC staining CDC45 in 293T cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 7. Flow cytometric analysis of 293 cells with CDC45 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. |
| 应用 | |
| 推荐剂量 | WB: 1:1000; IHC: 1:50-200; ICC/IF: 1:100-500; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Cell cycle events are regulated by the sequential activation and deactivation of cyclin dependent kinases (Cdks) and by the proteolysis of cyclins. The cell division cycle (Cdc) genes are required at various points in the cell cycle. Cdc25A, Cdc25B and Cdc25C protein tyrosine phosphatases function as mitotic activators by dephosphorylating Cdc2 p34 on regulatory tyrosine residues. Cdc6 and Cdc45 are the mammalian homologs of S. cerevisiae Cdc6 and Cdc45, which are involved in the initiation of DNA replication. Cdc37 appears to facilitate Cdk4/cyclin D1 complex formation and has been shown to form a stable complex with HSP 90. Cdc34, Cdc27 and Cdc16 function as ubiquitin-conjugating enzymes. Cdc34 is thought to be the structural and functional homolog of S. cerevisiae Cdc34, which is essential for the G1 to S phase transition. Cdc16 and Cdc27 are components of the APC (anaphase-promoting complex) which ubiquitinates cyclin B, resulting in cyclin B/Cdk complex degradation. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 66 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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