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别名 白细胞介素, interleukin 17A
Anti-IL-17 Antibody-HRP (1W700) 是一种 HRP-conjugated Mouse 抗体,靶向 IL-17。Anti-IL-17 Antibody-HRP (1W700) 可用于 ELISA。
Anti-IL-17 Antibody-HRP (1W700) 是一种 HRP-conjugated Mouse 抗体,靶向 IL-17。Anti-IL-17 Antibody-HRP (1W700) 可用于 ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μg | ¥ 2,485 | 5日内发货 |
| 产品描述 | Anti-IL-17 Antibody-HRP (1W700) is a HRP-conjugated Mouse antibody targeting IL-17. Anti-IL-17 Antibody-HRP (1W700) can be used in ELISA. |
| 别名 | 白细胞介素, interleukin 17A |
| Ig Type | Mouse IgG2a |
| 克隆号 | 1W700 |
| 交叉反应 | Human |
| 特异性 | Human IL-17A |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 0.1-1 μg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL17A/IL-17A/IL17 (rh IL17A/IL-17A/IL17; TMPY-02886; Q16552; Ile20-Ala155). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography and conjugated with horseradish-peroxidase (HRP). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation, and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophages, dendritic cells) and adaptive (T- and B-cells) immune systems. The IL-17 family of cytokines includes six members, IL-17/IL-17A, IL-17B, IL-17C, IL-17D, IL-17E/IL-25, and IL-17F, which are produced by multiple cell types. IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis, and multiple sclerosis.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| 偶联 | HRP |
| 其他可选修饰符 | Unconjugated/Biotin |
| 可提供抗体种类 | 3 |
| 免疫原 | Recombinant Protein: Human IL17A/IL-17A/IL17 Protein (TMPY-02886) |
| 抗原种属 | Human |
| 研究领域 | Neuroinflammation |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight. |
| 运输方式 | Shipping with blue ice. |
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