Name: SEMA7A Protein, Mouse, Recombinant (His)
Brand: TargetMol
SKU: TMPK-01216
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 259

3日内发货

10 μg

¥ 397

3日内发货

20 μg

¥ 658

3日内发货

50 μg

¥ 1,270

3日内发货

100 μg

¥ 2,130

现货

200 μg

¥ 3,880

5日内发货

500 μg

¥ 8,600

5日内发货

生物活性

产品描述	SEMA7A Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 69.5 kDa and the accession number is Q9QUR8.
生物活性	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景	Semaphorin7A (Sema7A) plays an important role in the immunoregulation of the brain.Sema7A is upregulated in the epileptic brain and plays a potential role in the regulation of seizure activity in PTZ-kindled epileptic rats, which may be related to neuroinflammation. Sema7A promotes the inflammatory cytokines TNF-α and IL-6 as well as the growth of mossy fibers through the ERK pathway, suggesting that Sema7A may promote seizures by increasing neuroinflammation and activating pathological neural circuits. Sema7A plays a critical role in epilepsy and could be a potential therapeutic target for this neurological disorder.
种属	Mouse
表达系统	HEK293 Cells
标签	C-His
蛋白编号	Q9QUR8
蛋白构建	Gln45-Ala646
蛋白纯度	> 95% as determined by Tris-Bis PAGE
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, 200 mM L-arginine (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名	Semaphorin-L, Semaphorin-K1, Semaphorin-7A, SEMAL, SEMAK1, Sema7A, Sema L, MGC126692, JMH, H-Sema-L, H-SEMA-K1, CDw108, CD108MGC126696, CD108
内毒素	< 1 EU/μg by the LAL method.

化学信息

分子量	69.5 kDa (predicted). Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

SEMA7A Protein, Mouse, Recombinant (His)

SEMA7A Protein, Mouse, Recombinant (His)

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